Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,191 questions · 2,354 findings · 362 reviews

No studies found 323 · 13.7%GRADE not reported 382 · 16.2%Very low 555 · 23.6%Low 597 · 25.4%Moderate 345 · 14.7%High 152 · 6.5%

Intervention not reported

Depression, SD units Investigators measured depression using a variety of scales. Lower scores represent improvement · people with dementia
1 finding from 1 review

Budesonide 10 mg vs prednisolone

Adverse event ‐ Reduction in plasma cortisol below lower reference limit · Adult patients with active ulcerative colitis

It is very uncertain whether budesonide 10 mg changes adverse event ‐ Reduction in plasma cortisol below lower reference… compared with prednisolone 40 mg (very low certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Condition‐specific anxiety symptoms As assessed by Y‐BOCS3 (scale from 0 to 40, better indicated by a lower score) · children and adolescents with anxiety disorders

It is very uncertain whether DCS and cognitive and behavioural therapies changes condition‐specific anxiety symptoms As assessed by Y‐BOCS3 (scale… compared with placebo and cognitive and behavioural therapies (very low certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Co‐morbid depression · children and adolescents with anxiety disorders

It is very uncertain whether DCS and cognitive and behavioural therapies changes co‐morbid symptoms of depression As assessed by CDI5 (scale from 0… compared with placebo and cognitive and behavioural therapies (very low certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Condition‐specific anxiety symptoms As assessed by LSAS5 (scale from: 0 to 144, better indicated by a lower score. 55 to 65 points = moderate social anxiety disorder (Liebowitz 1987)) · adults with anxiety disorders

DCS and cognitive and behavioural therapies showed no clear difference in condition‐specific anxiety symptoms As assessed by LSAS5 (scale… compared with placebo and cognitive and behavioural therapies (moderate certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Co‐morbid depression · adults with anxiety disorders

DCS and cognitive and behavioural therapies showed no clear difference in co‐morbid symptoms of depression As assessed by BDI‐II7 (scale from:… compared with placebo and cognitive and behavioural therapies (moderate certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Anxiety · adults with anxiety disorders

DCS and cognitive and behavioural therapies showed no clear difference in co‐morbid anxiety symptoms As assessed by BAI9 (scale from: 0 to 63,… compared with placebo and cognitive and behavioural therapies (low certainty).

1 finding from 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies

Quality of life Assessed by LIS (scale from: 0 to 48, better indicated by a lower score) · adults with anxiety disorders

It is very uncertain whether DCS and cognitive and behavioural therapies changes quality of life Assessed by LIS (scale from: 0 to 48, better… compared with placebo and cognitive and behavioural therapies (very low certainty).

1 finding from 1 review

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: lower tidal volume ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: lower tidal volume… compared with supine (moderate certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis
1 finding from 1 review

Intervention not reported

Respiratory symptoms (symptoms) Breathlessness, Cough and Sputum Scale Scale from 0 to 12. Lower score indicates fewer symptoms · individuals with stable bronchiectasis

The intervention showed no clear difference in respiratory symptoms (symptoms) Breathlessness, Cough and Sputum… (low certainty).

1 finding from 1 review