Question · asked by 1 review

DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies: Co‐morbid depression

It is very uncertain whether DCS and cognitive and behavioural therapies changes co‐morbid symptoms of depression As assessed by CDI5 (scale from 0… compared with placebo and cognitive and behavioural therapies (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
DCS and cognitive and behavioural therapies vs placebo and cognitive and behavioural therapies
Co‐morbid symptoms of depression As assessed by CDI5 (scale from 0 to 54, better indicated by a lower score) · Children and adolescents with anxiety disorders
It is very uncertain whether DCS and cognitive and behavioural therapies changes co‐morbid symptoms of depression As assessed by CDI5 (scale from 0… compared with placebo and cognitive and behavioural therapies (very low certainty).
Augmentation of cognitive and behavioural therapies (CBT) with d‐cycloserine for anxiety and related disorders (2015) · Cochrane Headline outcomes only
no estimate extracted3 studies · 114 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Augmentation of cognitive and behavioural therapies (CBT) with d‐cycloserine for anxiety and related disorders
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.