Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

774 questions · 787 findings · 58 reviews · Anaesthesia

No studies found 123 · 15.6%GRADE not reported 179 · 22.7%Very low 192 · 24.4%Low 188 · 23.9%Moderate 72 · 9.1%High 33 · 4.2%

Adverse effects of pharmacological intervention vs control

Cough · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Adverse effects of pharmacological intervention may leads to higher cough compared with control (low certainty).

1 finding from 1 review

Adverse effects of pharmacological intervention vs control

Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide

Adverse effects of pharmacological intervention showed no clear difference in pain on injection compared with control (low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Acute myocardial infarction · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes acute myocardial infarction compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Cardiac ischaemia indicated by ECG · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes cardiac ischaemia indicated by ECG compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Adverse effects: headache · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes side effect (headache) compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs placebo

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with placebo (very low certainty).

1 finding from 1 review

Nitroglycerin vs placebo

Acute myocardial infarction · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes acute myocardial infarction compared with placebo (very low certainty).

1 finding from 1 review