Question · asked by 1 review

Plain lidocaine vs buffered lidocaine: Injection site pain

Population
Patients requiring local anaesthesia
Intervention
Plain lidocaine
Comparison
buffered lidocaine
Outcome
Injection site pain

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Plain lidocaine vs buffered lidocaine
Pain at injection site VAS. Scale from 0 to 10. · Patients requiring local anaesthesia
Adjusting the pH of lidocaine for reducing pain on injection (2010) · Cochrane Headline outcomes only
no estimate extracted7 studies · 685 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adjusting the pH of lidocaine for reducing pain on injection
2010 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.