Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Laparoscopic vs hand‐assisted
Ureteric complications ‐ not reported · live donor nephrectomy (secondary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Laparoscopic vs hand‐assisted
Kidney function at one year ‐ not reported · live donor nephrectomy (secondary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Laparoscopic vs hand‐assisted
One‐year graft loss · live donor nephrectomy (secondary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
RR 1.31 [0.51, 3.37]2 studies · 230 participantsLow
Summary of findings table ‐ Open vs laparoscopic
Blood loss · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
no estimate extracted6 studies · 775 participantsModerate
Summary of findings table ‐ Open vs laparoscopic
Perioperative complications: pre 2010 · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
RR 0.66 [0.39, 1.11]4 studies · 464 participantsVery low
Summary of findings table ‐ Open vs laparoscopic
Perioperative complications: post 2010 · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
RR 2.19 [1.53, 3.13]2 studies · 303 participantsVery low
Summary of findings table ‐ Open vs laparoscopic
Perioperative complications: total · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
RR 1.02 [0.55, 1.89]6 studies · 767 participantsVery low
Summary of findings table ‐ Open vs laparoscopic
Reoperations · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
RR 0.57 [0.09, 3.64]6 studies · 596 participantsVery low
Summary of findings table ‐ Open vs laparoscopic
Warm ischaemia time · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
no estimate extracted7 studies · 815 participantsModerate
Summary of findings table ‐ Open vs laparoscopic
Hospital stay · live donor nephrectomy (primary outcomes)
Robotic versus laparoscopic versus open nephrectomy for live kidney donors (2024) · Cochrane
no estimate extracted6 studies · 775 participantsModerate
Dextranomer beads (autolytic) vs Eusol gauze
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 20 participantsVery low
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 40 participantsLow
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 28 participantsLow
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Time to a clean wound bed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 21 participantsLow
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 21 participantsVery low
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Time to a clean wound bed (minutes) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 106 participantsVery low
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Time to complete healing ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 106 participantsLow
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 40 participantsVery low
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Angiotensin‐converting‐enzyme inhibitors vs placebo or no treatment
All‐cause death Median · people with diabetes and kidney disease
Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of… (2024) · Cochrane
RR 0.91 [0.73, 1.15]24 studies · 7413 participantsLow
Angiotensin receptor blockers vs placebo or no treatment
Doubling of SCr Median · people with diabetes and kidney disease
Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of… (2024) · Cochrane
RR 0.84 [0.72, 0.97]4 studies · 3280 participantsLow
Angiotensin receptor blockers vs placebo or no treatment
Fatal or nonfatal stroke Median · people with diabetes and kidney disease
Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of… (2024) · Cochrane
RR 0.76 [0.32, 1.77]2 studies · 619 participantsLow
Angiotensin receptor blockers vs placebo or no treatment
Fatal or nonfatal myocardial infarction Median · people with diabetes and kidney disease
Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of… (2024) · Cochrane
RR 0.43 [0.11, 1.65]2 studies · 619 participantsLow