Denture use (prevalence) · Older people (aged 60 years or older) with dementia
Denture use was similar in older people with and without dementia, though one study reported lower denture use with more severe dementia; no meta-analysis was performed (ungraded).
1 finding from 1 review
Edentulousness (prevalence) · Older people (aged 60 years or older) with dementia
Edentulousness was similar in older people with and without dementia, with wide overlapping ranges across studies; no meta-analysis was performed (ungraded).
1 finding from 1 review
Orofacial pain (prevalence) · Older people (aged 60 years or older) with dementia
Orofacial pain prevalence was similar in older people with dementia (7.4 to 21.7%) and without dementia (6.7 to 18.5%), based on few studies; no meta-analysis was performed (ungraded).
1 finding from 1 review
Number of teeth · Older people (aged 60 years or older) with dementia
The number of teeth present was comparable between older people with and without dementia; no meta-analysis was performed (ungraded).
1 finding from 1 review
Dental caries · Children with exclusively primary dentition (age ≤71 months)
In a meta-analysis of two cross-sectional studies, breastfed children had lower odds of dental caries than bottle-fed children (OR 0.43, 95% CI 0.23 to 0.80); certainty was not formally graded.
2 findings from 1 review
OR 0.43 [0.23, 0.80]
2 studies · 620 participants
GRADE not reported
Breast and Bottle Feeding as Risk Factors for Dental Caries: A Systematic Review and Meta-Analysis. 2015 All outcomesKindergartens, hospitals and health centres; Kuwait, China, Syria, Sri Lanka, South Africa and Italy
Four studies showed that bottle fed children had more dental caries (p<0.05), while three studies found no such association (p>0.05); the review concluded that breastfeeding can protect against dental caries in early…
7 studies
GRADE not reported
Dental caries · Individuals of all ages
Individuals with Down syndrome had a lower prevalence of dental caries than those without (pooled OR 0.36, 95% CI 0.22 to 0.57; 2 studies; I2=0%); certainty of evidence not graded.
1 finding from 1 review
Metabolic syndrome (prevalent) · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Metabolic syndrome (prevalent): OR 0.49 (95% CI 0.38 to 0.64), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Diastolic blood pressure · Adults (general population)
Meta-analysis of randomised trials of vitamin D supplementation for Diastolic blood pressure: WMD -0.03 (95% CI -1.98 to 1.92), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
WMD -0.03 [-1.98, 1.92]
3 studies
GRADE not reported
Cardiovascular disease (prevalent) · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Cardiovascular disease (prevalent): OR 0.67 (95% CI 0.55 to 0.82), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Depression · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Depression (Cohort studies): HR 0.44 (95% CI 0.27 to 0.72), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
2 findings from 1 review
Systolic blood pressure · Adults (general population)
Meta-analysis of randomised trials of vitamin D supplementation for Systolic blood pressure: WMD -2.39 (95% CI -5.7 to 0.9), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
WMD -2.39 [-5.7, 0.9]
3 studies
GRADE not reported
Type 2 diabetes (prevalent) · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Type 2 diabetes (prevalent): OR 0.45 (95% CI 0.25 to 0.82), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Stainless steel crown preparation and placement deficiency · Alaska dental health aide therapists
No stainless steel crown preparation deficiencies were reported; placement deficiency was 3% for DHATs versus 9% for dentists, without a GRADE rating.
1 finding from 1 review
Intervention not reported
Technical performance / deficient preparations (DHATs)
1 finding from 1 review
Amalgam preparation deficiency · Alaska dental health aide therapists
Two of 13 DHAT amalgam preparations were deficient, without a GRADE rating.
1 finding from 1 review
Caries arrestment at the individual (patient) level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
Compared with other caries-management methods, SDF may increase caries arrestment at the individual level, but the pooled estimate is very imprecise (low certainty).
1 finding from 1 review
Caries arrestment at the individual (patient) level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
In one trial, SDF greatly increased individual-level caries arrestment versus ART/glass ionomer cement (OR 18.03); this subgroup was not separately GRADE-rated.
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
In one trial, SDF increased tooth-level caries arrestment versus 5% sodium fluoride varnish (OR 4.75; ungraded subgroup).
1 finding from 1 review
Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
Pooling two highly heterogeneous trials, SDF showed no significant difference versus 5% sodium fluoride varnish in surface-level caries arrestment (OR 1.46; ungraded subgroup).
1 finding from 1 review
Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
In one trial, nano-silver fluoride arrested more surfaces than SDF (OR 0.52 favoring the comparator; ungraded subgroup).
1 finding from 1 review