Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,340 questions · 1,512 findings · 205 reviews

No studies found 317 · 21%GRADE not reported 358 · 23.7%Very low 356 · 23.5%Low 271 · 17.9%Moderate 173 · 11.4%High 37 · 2.4%

Antibiotic prophylaxis vs placebo

SSSI · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis probably leads to lower SSSI compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

SSSI ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

Antibiotic prophylaxis showed no clear difference in SSSI ‐ low infection risk environment compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis vs placebo

SSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent probably leads to higher proportion of participants who were medication‐free (not using eye… compared with cataract surgery alone (moderate certainty).

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Glaucoma progression at 12 months, measured by additional visual field defects · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in health‐related quality of life · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who required further glaucoma surgery, including laser · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent may leads to lower proportion of participants who required further glaucoma surgery,… compared with cataract surgery alone (low certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Glaucoma progression at 12 months, measured by additional visual field defects · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in health‐related quality of life · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Proportion of participants who were medication‐free (not using eye drops) short‐term · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Hydrus microstent may leads to higher proportion of participants who were medication‐free (not using eye… compared with iStent trabecular micro‐bypass stent (low certainty).

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry short‐term · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review