Question · asked by 1 review

Antibiotic prophylaxis vs placebo: SSSI ‐ high infection risk environment

It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Antibiotic prophylaxis vs placebo
SSSI ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia…
It is very uncertain whether antibiotic prophylaxis changes SSSI ‐ high infection risk environment compared with placebo (very low certainty).
Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective… (2020) · Cochrane Headline outcomes only
RR 0.56 [0.41, 0.77]12 studies · 3163 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.