MRONJ (incidence proportion) · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
In both study arms, no case of postoperative MRONJ was observed (700 participants; 1 RCT); effect not estimable.
1 study · 700 participants
GRADE not reported
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether bone morphogenetic protein-2 (BMP-2) together with platelet-rich… changes healing of MRONJ compared with platelet-rich fibrin alone (very low certainty).
1 finding from 1 review
Pain (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction
It is very uncertain whether zinc oxide eugenol changes pain (VAS 0-10) compared with alvogyl (old formulation) (very low certainty).
1 finding from 1 review
Restoration survival · Children with decayed primary molar teeth
Multi-surface ART/HVGIC restorations had lower reported survival (49% at 3 years) than single-surface restorations (ungraded).
1 finding from 1 review
Survival rate (%) 49
9 studies
GRADE not reported
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine rinse (0.2%) pre- and post-extraction showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%) post-extraction only; GRADE not reported.
1 finding from 1 review
Mean time to resolution of pain · Adults (>18 years) with established dry socket following permanent tooth extraction
Neocone led to lower time to complete resolution of pain (days) compared with zinc oxide eugenol; GRADE not reported.
1 finding from 1 review
MRONJ (incidence proportion) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Metronidazole gel (25%, intrasocket) showed no clear difference in presence of dry socket compared with placebo gel; GRADE not reported.
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
A second meta-analysis reported odds ratios of 2.44 to 3.63 favouring 38% SDF over fluoride varnish/water for caries arrest (ungraded).
2 findings from 1 review
OR (caries arrest) OR 2.44-3.63 (range); 2.44 = Chu estimate including 30% SDF
3 studies
GRADE not reported
Proportion (caries arrest) 81 [68, 89]
12 studies
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Herbal mouthrinse showed no clear difference in presence of dry socket compared with chlorhexidine 0.2% mouthrinse; GRADE not reported.
1 finding from 1 review
Pain during the procedure (primary analysis) · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement
The reported estimate for procedural pain with ART versus conventional treatment was inconclusive (ungraded).
1 finding from 1 review
Restoration failure · Children (2-9 years) with caries in posterior primary teeth
Multi-surface ART restorations had a high reported mean annual failure rate (17%; ungraded).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Acellular dermal matrix led to lower presence of dry socket compared with control; GRADE not reported.
1 finding from 1 review
Restoration survival · Children with occlusoproximal caries in primary teeth
The reported pooled ART success estimate was 1.04.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Artemisia desertorum spreng (Yunnan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Acellular dermal matrix patch led to lower presence of dry socket compared with no treatment; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine 0.2% socket irrigation (monoject syringe) led to lower presence of dry socket compared with chlorhexidine 0.2% mouthrinse; GRADE not reported.
1 finding from 1 review
Adverse events: gingival bleeding · Children (3-10 years) with dentine caries in primary molars
The reported estimate for gingival bleeding with preformed metal crowns was inconclusive (ungraded).
1 finding from 1 review
RR 1.09 [0.42, 2.86]
2 studies
GRADE not reported