Question · asked by 1 review

Zinc oxide and eugenol (ZOE) vs Alvogyl (old formulation): Pain (VAS 0-10)

Population
Adults (>18 years) with established dry socket following permanent tooth extraction
Intervention
Zinc oxide and eugenol (ZOE)
Comparison
Alvogyl (old formulation)
Outcome
Pain (VAS 0-10)

It is very uncertain whether zinc oxide eugenol changes pain (VAS 0-10) compared with alvogyl (old formulation) (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Zinc oxide eugenol vs Alvogyl (old formulation)
Pain (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction · Day 7
It is very uncertain whether zinc oxide eugenol changes pain (VAS 0-10) compared with alvogyl (old formulation) (very low certainty).
Local interventions for the management of alveolar osteitis (dry socket) (2022) · Cochrane All outcomes
MD 1.40 [1.04, 1.75]2 studies · 80 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Local interventions for the management of alveolar osteitis (dry socket)
2022 · Cochrane All outcomes
2021-09Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.