Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Low periodontal-disease prevalence vs Not applicable

Oral health-related quality of life · people aged 60 years and older living in the community

No statistically significant difference in OHRQoL was reported by periodontal-disease prevalence.

1 finding from 1 review

Flowable bulk-fill composite resin vs Light-cured compomer (polyacid-modified composite resin)

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; both arms had 0% failure.

1 finding from 1 review

Laser (low-level laser) at P6 point vs sham control

Reduction in gagging (assessor-reported) · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled children

It is very uncertain whether laser (low-level laser) at P6 point changes reduction in gagging (assessor-reported) compared with control (sham/dummy laser) (very low certainty).

1 finding from 1 review

CD4+ T-cell count below 250 cells/mm3

HIV-related oral lesions · Children living with HIV receiving ART

One reported study did not show a clear difference in HIV-related oral lesions for children with CD4+ T-cell counts below 250 cells/mm3.

2 findings from 1 review

Comparison 7: Structured GP follow‐up vs TAU or another comparator

Repetition of SH at post‐intervention · self‐harm in adults

Comparison 7: Structured GP follow‐up showed no clear difference in repetition of SH at post‐intervention (hospital records) compared with TAU or another comparator (low certainty).

2 findings from 1 review