Cochrane · systematic review · CD007689

Acupuncture for polycystic ovarian syndrome

Lim, CED, Ng, RWC, Cheng, NCL, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
27
current version
GRADE rated
16
No studies
11
Included studies
NR
No studies 11 · 40.7%Ungraded 0 · 0%Very low 9 · 33.3%Low 6 · 22.2%Moderate 1 · 3.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

True acupuncture compared to sham acupuncture for polycystic ovarian syndrome

Population: polycystic ovarian syndrome
7 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate
True acupuncture vs sham acupuncture
RR 0.97 [0.76, 1.24]1 study · 926 participantsLow
Downgraded: risk of bias, imprecision
Multiple pregnancy rate
True acupuncture vs sham acupuncture
RR 0.89 [0.33, 2.45]1 study · 926 participantsLow
Downgraded: risk of bias, imprecision
Ovulation rate
True acupuncture vs sham acupuncture
no estimate extracted2 studies · 1010 participantsLow
Downgraded: risk of bias, imprecision
Clinical pregnancy rate
True acupuncture vs sham acupuncture
RR 1.03 [0.82, 1.29]3 studies · 1117 participantsLow
Downgraded: risk of bias, imprecision
Restored regular menstrual period
True acupuncture vs sham acupuncture
no estimate extracted1 study · 141 participantsLow
Downgraded: imprecision
Miscarriage rate
True acupuncture vs sham acupuncture
RR 1.1 [0.77, 1.56]1 study · 926 participantsLow
Downgraded: risk of bias, imprecision
Adverse events
True acupuncture vs sham acupuncture
RR 1.16 [1.02, 1.31]3 studies · 1230 participantsModerate
Downgraded: risk of bias

Low‐frequency electroacupuncture compared to physical exercise or no intervention for polycystic ovarian syndrome

Population: polycystic ovarian syndrome
6 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate
Low‐frequency electroacupuncture vs physical exercise or no intervention
no estimate extractedNRNo studies
Multiple pregnancy rate
Low‐frequency electroacupuncture vs physical exercise or no intervention
no estimate extractedNRNo studies
Ovulation rate
Low‐frequency electroacupuncture vs physical exercise or no intervention
no estimate extractedNRNo studies
Restored regular menstrual period – low‐frequency electroacupuncture vs physical exercise
Low‐frequency electroacupuncture vs physical exercise or no intervention
MD 0.221 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Restored regular menstrual period – low‐frequency electroacupuncture vs no intervention
Low‐frequency electroacupuncture vs physical exercise or no intervention
MD 0.371 study · 31 participantsVery low
Downgraded: risk of bias, imprecision
Adverse eventsc
Low‐frequency electroacupuncture vs physical exercise or no intervention
RR 4.46 [0.77, 25.78]1 study · 201 participantsVery low
Downgraded: risk of bias, imprecision

True acupuncture compared to relaxation for polycystic ovarian syndrome

Population: polycystic ovarian syndrome
4 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate
True acupuncture vs relaxation
no estimate extractedNRNo studies
Multiple pregnancy rate
True acupuncture vs relaxation
no estimate extractedNRNo studies
Ovulation rate
True acupuncture vs relaxation
no estimate extracted1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
True acupuncture vs relaxation
no estimate extractedNRNo studies

True acupuncture compared to clomiphene for polycystic ovarian syndrome

Population: polycystic ovarian syndrome
6 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate
True acupuncture vs clomiphene
no estimate extractedNRNo studies
Multiple pregnancy rate
True acupuncture vs clomiphene
no estimate extractedNRNo studies
Ovulation rate
True acupuncture vs clomiphene
no estimate extractedNRNo studies
Restored regular menstrual period – restored menstruation at the end of treatment
True acupuncture vs clomiphene
RR 1.64 [0.94, 2.85]1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision
Restored regular menstrual period – restored menstruation 1 month after end of treatment
True acupuncture vs clomiphene
RR 1.5 [1.03, 2.19]1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
True acupuncture vs clomiphene
RR 1.33 [0.3, 5.83]1 study · 120 participantsVery low
Downgraded: risk of bias, imprecision

True acupuncture compared to Diane‐35 for polycystic ovarian syndrome

Population: polycystic ovarian syndrome
4 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate
True acupuncture vs Diane‐35
no estimate extractedNRNo studies
Multiple pregnancy rate
True acupuncture vs Diane‐35
no estimate extractedNRNo studies
Ovulation rate
True acupuncture vs Diane‐35
RR 1.45 [0.87, 2.42]1 study · 68 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
True acupuncture vs Diane‐35
RR 0.7 [0.25, 1.99]2 studies · 360 participantsVery low
Downgraded: risk of bias, imprecision