Findings

What do systematic reviews say?

3,747 questions · 3,943 findings · 594 reviews

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No studies found 784 · 19.9%GRADE not reported 530 · 13.4%Very low 1,040 · 26.4%Low 981 · 24.9%Moderate 444 · 11.3%High 164 · 4.2%

Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open)

Reoperation rate · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 107 participants
Very low

Amphotericin B vs placebo or no treatment

Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy

Amphotericin B showed no clear difference in oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Interventions for preventing oral candidiasis for patients with cancer receiving treatment 2007 · Cochrane All outcomes
RR 0.46 [0.18, 1.23]
2 studies · 48 participants
GRADE not reported

Triclosan rinse vs Saline rinse

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Triclosan rinse led to lower duration of ICU stay compared with saline rinse; GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
MD -4.97 [-5.55, -4.39]
1 study · 324 participants
GRADE not reported

Triclosan rinse vs Saline rinse

Duration of mechanical ventilation · Critically ill patients receiving mechanical ventilation in ICU

Triclosan rinse led to lower duration of mechanical ventilation compared with saline rinse; GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
MD -5.24 [-5.64, -4.84]
1 study · 324 participants
GRADE not reported

Triclosan rinse vs Saline rinse

Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU

Triclosan rinse showed no clear difference in incidence of VAP compared with saline rinse; GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
RR 0.89 [0.71, 1.12]
1 study · 324 participants
GRADE not reported

Nasogastric tubes vs no enteral tube feeding

Pressure ulcers · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nasogastric tubes vs no enteral tube feeding

Pain and comfort · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nasogastric tubes vs no enteral tube feeding

Improvement of nutritional parameters (nutrition)d · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Very low

Nasogastric tubes vs no enteral tube feeding

Survival time · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nasogastric tubes vs no enteral tube feeding

Total mortalitya · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 236 participants
Very low

Nasogastric tubes vs no enteral tube feeding

Quality of life · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral ferric maltol vs oral placebo

Serious adverse events ‐ mild disease to quiescent (up to 52 weeks) · IBD patients

It is very uncertain whether oral ferric maltol changes serious adverse events ‐ mild disease to quiescent (up to 52 weeks) compared with oral placebo (very low certainty).

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
RR 1 [0.15, 6.88]
1 study · 128 participants
Very low

Oral ferric maltol vs oral placebo

Number of responders · IBD patients

It is very uncertain whether oral ferric maltol changes number of responders ‐ mild disease to quiescent (up to 52 weeks) compared with oral placebo (very low certainty).

1 finding from 1 review

Interventions for treating iron deficiency anaemia in inflammatory bowel disease 2021 · Cochrane Headline outcomes only
RR 73 [4.58, 1164.36]
1 study · 128 participants
Very low

ACT price vouchers vs no subsidies

ACT access (percentage of illness episodes treated with ACTs; all age groups) · Patients seeking treatment for suspected uncomplicated malaria

1 finding from 1 review

Subsidising artemisinin‐based combination therapy in the private retail sector 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2789 participants
High

ACT price vouchers vs no subsidies

ACT targeting (percentage of ACT takers who are malaria positive; all age groups) · Patients seeking treatment for suspected uncomplicated malaria

1 finding from 1 review

Subsidising artemisinin‐based combination therapy in the private retail sector 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 2789 participants
High

Trichuris suis eggs vs placebo

Clinical remission · patients with induction of remission in ulcerative colitis

Trichuris suis eggs showed no clear difference in clinical remission compared with placebo (low certainty).

1 finding from 1 review

Helminth therapy (worms) for induction of remission in inflammatory bowel disease 2014 · Cochrane Headline outcomes only
RR 2.4 [0.27, 21.63]
1 study · 54 participants
Low

Trichuris suis eggs vs placebo

Clinical improvement at 12 weeks · patients with induction of remission in ulcerative colitis

Trichuris suis eggs showed no clear difference in clinical improvement at 12 weeks compared with placebo (low certainty).

1 finding from 1 review

Helminth therapy (worms) for induction of remission in inflammatory bowel disease 2014 · Cochrane Headline outcomes only
RR 2.6 [0.97, 6.95]
1 study · 54 participants
Low

Platelet-rich fibrin (PRF) graft vs control

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

Platelet rich fibrin showed no clear difference in presence of dry socket compared with control; GRADE not reported.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Follow-up: median 7 days
RR 0.44 [0.15, 1.35]
1 study · 100 participants
GRADE not reported

Autologous platelet‐rich plasma vs placebo or no treatment

Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Follow-up: median 7 days
RR 0.51 [0.19, 1.33]
2 studies · 127 participants
Very low

Autologous platelet‐rich plasma vs placebo or no treatment

Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Follow-up: median 7 days
No adverse events were reported in these two trials.
2 studies
GRADE not reported