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Evidence found and GRADE certainty

1,245 questions · 1,274 findings · 321 reviews

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No studies found 247 · 19.4%GRADE not reported 195 · 15.3%Very low 372 · 29.2%Low 282 · 22.1%Moderate 141 · 11.1%High 37 · 2.9%

Additional radon in carbon dioxide baths vs carbon dioxide baths only

Improvement More than 1 category change in pain intensity on 4‐point scale (no pain/sporadic/daily/continuous) · patients with rheumatoid arthritis

Additional radon in carbon dioxide baths showed no clear difference in improvement More than 1 category change in pain intensity on 4‐point… compared with carbon dioxide baths only (low certainty).

2 findings from 1 review

Massage vs inactive control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with LBP
1 finding from 1 review

Massage vs active control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with LBP
1 finding from 1 review

Laparoscopic fundoplication vs medical management

(5 years or more) · Patients with gastro‐oesophageal reflux disease (GORD) in adults

It is very uncertain whether laparoscopic fundoplication changes (5 years or more) compared with medical management (very low certainty).

1 finding from 1 review

Transmyocardial laser revascularization vs medical treatment

Angina reduction ‐ NYHA scale Decrease in two angina classes or more · patients with refractory angina

Transmyocardial laser revascularization may leads to higher angina reduction Decrease in two angina classes or more compared with medical treatment (low certainty).

2 findings from 1 review

Transmyocardial laser revascularization vs medical treatment

Angina reduction ‐ CCS score Decrease in two angina classes or more · patients with refractory angina

Transmyocardial laser revascularization may leads to higher angina reduction ‐ CCS score Decrease in two angina classes or more compared with medical treatment (low certainty).

1 finding from 1 review

Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo)

Maternal anaemia at term (Hb less than 110 g/L at 37 weeks' gestation or more) (ALL) · pregnant women

(Maternal outcomes) Any supplements containing iron and folic acid probably leads to lower maternal anaemia at term (Hb less than 110 g/L at 37 weeks'… compared with same supplements without iron nor folic acid (no iron nor folic acid… (moderate certainty).

1 finding from 1 review

Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo)

Iron deficiency at term (as defined by trialists, based on any indicator of iron status at 37 wk gestation or more) · pregnant women

(Maternal outcomes) Any supplements containing iron and folic acid may leads to lower maternal iron deficiency at term (as defined by trialists, based on… compared with same supplements without iron nor folic acid (no iron nor folic acid… (low certainty).

1 finding from 1 review

Any supplements containing iron vs same supplements without iron or no treatment/placebo (no iron or placebo)

Maternal anaemia at term (Hb less than 110 g/L at 37 weeks' gestation or more) (ALL) · pregnant women

(Maternal outcomes) Any supplements containing iron may leads to lower maternal anaemia at term (Hb less than 110 g/L at 37 weeks'… compared with same supplements without iron or no treatment/placebo (no iron or… (low certainty).

1 finding from 1 review

Any supplements containing iron vs same supplements without iron or no treatment/placebo (no iron or placebo)

Iron deficiency at term (as defined by trialists, based on any indicator of iron status at 37 wk gestation or more) · pregnant women

(Maternal outcomes) Any supplements containing iron may leads to lower maternal iron deficiency at term (as defined by as defined by… compared with same supplements without iron or no treatment/placebo (no iron or… (low certainty).

1 finding from 1 review

Specialised antenatal clinics vs usual care

Postnatal depression · Women with a multiple pregnancy

It is very uncertain whether specialised antenatal clinics changes postnatal depression (6 months' postpartum). EPDS score 13 or more. compared with standard care (very low certainty).

1 finding from 1 review