Cochrane · systematic review · CD006106
Pain relief in hysterosalpingography
Hindocha, A, Beere, L, O'Flynn, H, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
19
current version
GRADE rated
19
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 26.3%Low 11 · 57.9%Moderate 3 · 15.8%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Topical anaesthetic versus placebo or no treatment for pain relief in hysterosalpingography
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean Pain Score During HSG VAS Scale (0 to 10) Topical anaesthetic vs placebo or no treatment | no estimate extracted | 9 studies · 613 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Mean Pain Score Less Than 30 minutes After HSG Visual analogue Scale (0 to 10) Topical anaesthetic vs placebo or no treatment | no estimate extracted | 5 studies · 373 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Mean Pain Score More Than 30 minutes After HSG Visual analogue Scale (0 to 10) Topical anaesthetic vs placebo or no treatment | no estimate extracted | 2 studies · 166 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Oral opioid analgesics versus placebo or no treatment for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean Pain Score During HSG Visual analogue Scale (0 to 10) Oral opioid analgesics vs placebo or no treatment | no estimate extracted | 1 study · 128 participants | Low Downgraded: risk of bias, inconsistency, indirectness, publication bias |
Mean Pain Score More Than 30 minutes After HSG Visual analogue scale (0 to 10) Oral opioid analgesics vs placebo or no treatment | no estimate extracted | 1 study · 128 participants | Moderate Downgraded: risk of bias, inconsistency, indirectness, publication bias |
Intravenous opioid analgesics versus placebo or no treatment for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean Pain Score During HSG Visual analogue scale (10 cm) Intravenous opioid analgesics vs placebo or no treatment | no estimate extracted | 1 study · 62 participants | Moderate Downgraded: risk of bias, indirectness, publication bias |
Oral non‐opioid analgesics versus placebo or no treatment for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain Score During HSG Visual analogue scale (0 to 10) Oral non‐opioid analgesics vs placebo or no treatment | no estimate extracted | 3 studies · 133 participants | Low Downgraded: risk of bias, inconsistency, indirectness, publication bias |
Pain Score Less Than 30 minutes After HSG Visual analogue scale (0 to 10) Oral non‐opioid analgesics vs placebo or no treatment | no estimate extracted | 2 studies · 45 participants | Very low Downgraded: risk of bias, inconsistency, indirectness, publication bias |
Mean Pain Score More Than 30 minutes After HSG Visual analogue Scale (0 to 10) Oral non‐opioid analgesics vs placebo or no treatment | no estimate extracted | 3 studies · 133 participants | Low Downgraded: risk of bias, inconsistency, indirectness, publication bias |
Locally injected anaesthetics versus placebo or no treatment for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean Pain Score During HSG Visual analogue scale Locally injected anaesthetics vs placebo or no treatment | no estimate extracted | 2 studies · 125 participants | Low Downgraded: risk of bias |
Mean Pain Score Less Than 30 minutes After HSG Visual analogue scale Locally injected anaesthetics vs placebo or no treatment | no estimate extracted | 2 studies · 125 participants | Low Downgraded: risk of bias |
Opioid versus non‐opioid analgesics for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean Pain Score During HSG Visual analogue Scale (0 to 10) Opioid vs non‐opioid analgesics | no estimate extracted | 1 study · 91 participants | Low Downgraded: risk of bias, imprecision, indirectness, publication bias |
Mean Pain Score Less Than 30 minutes After HSG Visual analogue Scale (0 to 10) Opioid vs non‐opioid analgesics | no estimate extracted | 1 study · 91 participants | Low Downgraded: risk of bias, imprecision, indirectness, publication bias |
Mean Pain Score More Than 30 minutes After HSG Visual analogue Scale (0 to 10) Opioid vs non‐opioid analgesics | no estimate extracted | 1 study · 91 participants | Low Downgraded: risk of bias, imprecision, indirectness, publication bias |
Topical anaesthetic versus paracervical block for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean Pain Score During HSG Visual analogue scale (0 to 10) Topical anaesthetic vs paracervical block | no estimate extracted | 1 study · 20 participants | Moderate Downgraded: risk of bias, imprecision, indirectness, publication bias |
Mean Pain Score Less Than 30 minutes After HSG Visual analogue scale (0 to 10) Topical anaesthetic vs paracervical block | no estimate extracted | 1 study · 20 participants | Low Downgraded: risk of bias, imprecision, indirectness, publication bias |
Mean Pain Score More Than 30 minutes After HSG Visual analogue scale (0 to 10) Topical anaesthetic vs paracervical block | no estimate extracted | 1 study · 20 participants | Low Downgraded: risk of bias, imprecision, indirectness, publication bias |
Topical anaesthetic versus non‐opioid analgesics for pain relief in HSG
Population: Women being investigated for infertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mean pain score within 30 minutes after HSG Visual analogue scale Topical anaesthetic vs non‐opioid analgesics | no estimate extracted | 1 study · 100 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Mean pain score more than 30 minutes after HSG Visual analogue scale Topical anaesthetic vs non‐opioid analgesics | no estimate extracted | 1 study · 100 participants | Very low Downgraded: risk of bias, imprecision, indirectness |