Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

hCG vs no ovulation trigger

Miscarriage per clinical pregnancy · women with anovulatory infertility undergoing ovulation induction with clomiphene citrate

Human chorionic gonadotrophin showed no clear difference in miscarriage rate per clinical pregnancy Spontaneous pregnancy loss… compared with no ovulation trigger (low certainty).

1 finding from 1 review

Short interval vs long interval

Pregnancy rate · women trying to conceive by intrauterine insemination

Short interval may leads to lower pregnancy rate per couple ‐ 24 hours versus 34 to 36 hours compared with long interval (low certainty).

3 findings from 1 review

Short interval vs long interval

Miscarriage · women trying to conceive by intrauterine insemination

It is very uncertain whether short interval changes miscarriage rate per pregnancy ‐ 24 hours versus 34 to 36 hours compared with long interval (very low certainty).

3 findings from 1 review

Intervention not reported

Pregnancy rate per couple · women undergoing intrauterine insemination

It is very uncertain whether the intervention changes pregnancy rate per couple (very low certainty).

1 finding from 1 review

GnRHa depot vs GnRHa daily injection

Ongoing pregnancy / live birth rate per woman · women undergoing pituitary suppression in assisted reproduction

GnRHa depot showed no clear difference in live birth/ongoing pregnancy rate per woman Delivery of one or more… compared with gnRHa daily injection (low certainty).

1 finding from 1 review

GnRHa depot vs GnRHa daily injection

Clinical pregnancy rate · women undergoing pituitary suppression in assisted reproduction

GnRHa depot showed no clear difference in clinical pregnancy rate per woman Identified by the presence of a… compared with gnRHa daily injection (moderate certainty).

1 finding from 1 review