Chronic herpes simplex infection (WHO clinical stage 4) · Children or adolescents
No eligible studies reported chronic herpes simplex infection.
1 finding from 1 review
Acute necrotising ulcerative periodontitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in acute necrotising ulcerative periodontitis between ART regimens (very low certainty).
1 finding from 1 review
Periodontal disease prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
ART was not associated with a significant difference in periodontal disease prevalence among CLWH (very low certainty).
1 finding from 1 review
Kaposi's sarcoma prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
Kaposi's sarcoma was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty).
1 finding from 1 review
OR 0.00 [0.00, 0.03]
Studies not reported
Very low
Kaposi's sarcoma prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in kaposi's sarcoma between ART regimens (very low certainty).
1 finding from 1 review
Linear gingival erythema prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in linear gingival erythema between ART regimens (very low certainty).
1 finding from 1 review
Persistent parotid enlargement (WHO clinical stage 2) · Children or adolescents
No significant difference in persistent parotid enlargement between groups (OR 10.36, 95% CI 0.53 to 201.45; single study, very imprecise).
1 finding from 1 review
Chronic herpes simplex infection prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in chronic herpes simplex infection between ART regimens (very low certainty).
1 finding from 1 review
Angular cheilitis (WHO clinical stage 2) · Children or adolescents
No significant difference in angular cheilitis prevalence between CLWH and healthy controls (pooled OR 1.95, 95% CI 0.16 to 23.65).
1 finding from 1 review
Mucosal hyperpigmentation prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in mucosal hyperpigmentation between CLWH with and without ART (very low certainty).
1 finding from 1 review
OR 1.79 [0.89, 3.61]
Studies not reported
Very low
Gingivitis · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in gingivitis between ART regimens (very low certainty).
1 finding from 1 review
Chronic herpes simplex infection prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in chronic herpes simplex infection between CLWH with and without ART (very low certainty).
1 finding from 1 review
OR 2.47 [0.88, 6.97]
Studies not reported
Very low
Linear gingival erythema (WHO clinical stage 2) · Children or adolescents
No difference in linear gingival erythema between groups (pooled OR 1.00, 95% CI 0.06 to 16.19); the lesion was essentially absent in both groups.
1 finding from 1 review
Caries experience · Children and adolescents (<18 years) living with HIV (CLWH)
ART was not associated with a significant difference in dental caries experience among CLWH (very low certainty).
1 finding from 1 review
Persistent parotid enlargement prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in persistent parotid enlargement between ART regimens (very low certainty).
1 finding from 1 review
Dental caries (by severity) · Children or adolescents
One study reported higher median caries severity among CLWH under 12 years; no meta-analytic estimate was pooled.
1 finding from 1 review
Dental caries prevalence · Preschool children attending Al Ain pediatric dentistry department
Dental caries prevalence was 99.4%.
1 finding from 1 review
Severe early childhood caries · Children aged 5-6 years in Ajman schools
High snack consumption was associated with higher odds of severe early childhood caries.
1 finding from 1 review
Probing pocket depth · Adults (general and hospital populations assessed in case-control studies)
Probing depth is significantly increased in systemic sclerosis patients (SMD 3.10) with very high heterogeneity; certainty ungraded.
3 findings from 1 review
SMD 3.101 [1.374, 4.829]
7 studies
GRADE not reported
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. 2021 All outcomesHospital/clinic-based case-control studies from Asia, America and Europe · Other/non-Asia (Da Silva 2019, Iordache 2019, Isola 2017, Pischon 2016)
SMD 4.86 [1.61, 8.10]
4 studies
GRADE not reported
Oral manifestations of patients with systemic sclerosis: a meta-analysis for case-controlled studies. 2021 All outcomesHospital/clinic-based case-control studies from Asia, America and Europe · Asia (Elimelech 2015, Leung 2011, Mayer 2013)
SMD 1.113 [0.751, 1.476]
3 studies
GRADE not reported
Dental caries prevalence · Preschool children in Sharjah day cares
Caries prevalence was 77% in private day cares versus 22% in public day cares.
2 findings from 1 review