Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,127 questions · 1,590 findings · 132 reviews · Oral Health

No studies found 189 · 11.9%GRADE not reported 1,166 · 73.3%Very low 130 · 8.2%Low 69 · 4.3%Moderate 25 · 1.6%High 11 · 0.7%

High intake of sweets vs Lower/less intake of sweets

Dental caries · Primary school children in Ethiopia

A high intake of sweets was associated with higher odds of dental caries (OR 2.71, 95% CI 1.968-3.451; ungraded).

1 finding from 1 review

Higher BMI (continuous / per-unit increment) vs Lower BMI (continuous reference / per 1 kg/m2 decrement)

Dental caries in children · Children (approx. 4-18 years)

Pooling studies that used BMI as a continuous variable showed no significant association between per-unit BMI and childhood dental caries (OR 1.01, 95% CI 0.99 to 1.03; I2=3.5%); ungraded.

3 findings from 1 review

Superelastic NiTi arch wire vs Conventional (stabilised) NiTi arch wire

Time to next/working arch wire · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

Superelastic NiTi arch wire showed no clear difference in time to next/working arch wire compared with conventional (stabilised) NiTi arch wire; GRADE not reported.

1 finding from 1 review

Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate)

Association between orthodontic treatment duration and ICLs incidence · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new ICLs

ICLs incidence increased with longer orthodontic treatment duration (meta-regression P<.01; ungraded).

1 finding from 1 review

High-frequency sugar consumption (three or more times daily) vs Low sugar intake (fewer than three times daily)

Dental caries in permanent teeth · Nigerian individuals with permanent dentition (approximately 12 years and older)

In permanent dentition, high-frequency sugar consumption was associated with non-significant 15% higher odds of caries (OR 1.15, 95% CI 0.88 to 1.52), with no heterogeneity (I2=0%; ungraded).

1 finding from 1 review

Thermoelastic copper NiTi (CuNiTi) arch wire vs Conventional (stabilised) NiTi arch wire

Time to alignment · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)

Thermoelastic copper NiTi (CuNiTi) arch wire showed no clear difference in time to alignment (alignment rate ratio) compared with conventional NiTi arch wire (low certainty).

1 finding from 1 review

Higher waist circumference vs Lower waist circumference

Dental caries in children · Children (approx. 4-18 years)

Waist circumference was not significantly associated with childhood dental caries (pooled OR 1.08, 95% CI 0.90 to 1.30; I2=47.7%); ungraded.

1 finding from 1 review

Superelastic NiTi arch wire vs Titanium-niobium-tantalum-zirconium (TiNbTaZr) arch wire

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review

Coated superelastic NiTi wire (BioCosmetic, Titanol, TP Aesthetic or Tooth Tone) vs A different coated superelastic NiTi wire

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review

Multistrand stainless steel wire vs Wires of other materials (conventional stainless steel, superelastic NiTi, thermoelastic NiTi)

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
  • Initial arch wires used in orthodontic treatment with fixed appliances 2024 · Cochrane All outcomes
    6 weeks to 6 months
    Multistrand StSt versus other materials (conventional StSt, superelastic NiTi, thermoelastic NiTi); alignment rate not pooled due to clinical heterogeneity (Cobb 1998; Evans 1998; Quintao 2005; West 1995); results…
    4 studies · 281 participants
    Very low