Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Moderate‐severe neurodevelopmental impairment at 18 to 26 months ‐ not measured · health problem or population

The review found no eligible studies for this question.

2 findings from 1 review

Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels

Combined outcome of mortality or BPD at 36 weeks' PMA · health problem or population

It is very uncertain whether summary of Findings Table ‐ Low changes death or BPD at 36 weeks' PMA compared with moderate‐high nasal continuous positive airway pressure levels (very low certainty).

1 finding from 1 review

Enteral zinc supplementation vs no zinc supplementation

All‐cause mortality (between start of intervention and end of · preterm infants

Enteral zinc supplementation may leads to lower all‐cause mortality (between start of intervention and end of compared with no zinc supplementation (low certainty).

1 finding from 1 review

Indomethacin vs placebo or control

Failure of PDA closure within 1 week of administration of the first dose of indomethacin · symptomatic patent ductus arteriosus in preterm infants

Indomethacin leads to lower failure of PDA closure within 1 week of administration of the first… compared with placebo or control (high certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs no treatment

Rate of rehospitalization within 7 days of discharge for treatment for hyperbilirubinemia · term and late preterm neonates

It is very uncertain whether sunlight (with or without filters or amplification) changes rate of rehospitalization within 7 days of discharge for treatment… compared with no treatment (very low certainty).

1 finding from 1 review