Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

624 questions · 782 findings · 62 reviews

No studies found 13 · 1.7%GRADE not reported 657 · 84%Very low 76 · 9.7%Low 23 · 2.9%Moderate 13 · 1.7%High 0 · 0%

Dementia (any type or severity) vs Older people without dementia

Caries experience (mean DMFT) · Older people (aged 60 years or older) with dementia

The DMFT index was similar between groups, with only 1 of 5 comparative studies finding a significant difference; no meta-analysis was performed (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Denture use (prevalence) · Older people (aged 60 years or older) with dementia

Denture use was similar in older people with and without dementia, though one study reported lower denture use with more severe dementia; no meta-analysis was performed (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Dental caries: prevalence of root caries · Older people (aged 60 years or older) with dementia

Root caries was higher in older people with dementia (0.6 to 4.9) than without (0.3 to 1.7), described as significantly more common but not pooled (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Edentulousness (prevalence) · Older people (aged 60 years or older) with dementia

Edentulousness was similar in older people with and without dementia, with wide overlapping ranges across studies; no meta-analysis was performed (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Orofacial pain (prevalence) · Older people (aged 60 years or older) with dementia

Orofacial pain prevalence was similar in older people with dementia (7.4 to 21.7%) and without dementia (6.7 to 18.5%), based on few studies; no meta-analysis was performed (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Coronal caries (mean number) · Older people (aged 60 years or older) with dementia

Coronal caries was higher in older people with dementia (0.1 to 2.9) than without (0.0 to 1.0), described as significantly more common but not pooled (ungraded).

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Number of teeth · Older people (aged 60 years or older) with dementia

The number of teeth present was comparable between older people with and without dementia; no meta-analysis was performed (ungraded).

1 finding from 1 review

Job-related or family-related stress and pessimistic attitude to life vs Lower stress and no pessimistic attitude

Periodontal disease and serum IL-1β IL-6 and cortisol · Patients with aggressive or chronic periodontitis at a university periodontology department

No correlation was reported between immunological markers cortisol and registered stress values; untreated aggressive periodontitis was accompanied by pessimistic attitude and elevated serum IL-6.

1 finding from 1 review

Perceived psychosocial stress vs No or lower perceived stress

GCF elastase activity and non-surgical periodontal treatment outcome (salivary cortisol, ICTP measured; no effect reported) · Adults with periodontitis needing non-surgical periodontal treatment

In one 6-month longitudinal study, patients under psychosocial stress had higher gingival crevicular fluid elastase and poorer outcomes after non-surgical periodontal therapy; not pooled (ungraded).

1 finding from 1 review

Depression and social isolation (psychosocial strain) vs No depression or lower psychosocial strain

Antibody titres to periodontal pathogens · Adults with periodontitis

In one case-control study, depression as a marker of social isolation was associated with elevated antibody titres to periodontal pathogens at baseline and 1-year follow-up; not pooled (ungraded).

1 finding from 1 review

Intervention not reported

Serum inflammatory cytokines (IL-1b, IL-6) and cortisol in periodontitis
1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Mean number of decayed teeth (mean DT) · Older people (aged 60 years or older) with dementia

Decayed-teeth values varied across studies and were not meta-analyzed.

1 finding from 1 review

Dementia (any type or severity) vs Older people without dementia

Patient outcomes: mean number of filled teeth per 0- to 15-year-old · Older people (aged 60 years or older) with dementia

Filled-teeth values varied across studies and were not meta-analyzed.

1 finding from 1 review

High maternal allostatic load (chronic stress) and low socioeconomic status vs Lower maternal allostatic load

Dental caries in children · Mother-child pairs

In one cross-sectional study, higher maternal allostatic load was associated with child dental caries experience and with health-related maternal care-taking behaviours; not pooled (ungraded).

1 finding from 1 review

Low socioeconomic status and family financial stress vs Higher socioeconomic status and lower stress

Salivary cortisol, cariogenic bacterial load and dental caries · Kindergarten-age children

In one cross-sectional study of children, low socioeconomic status, higher basal salivary cortisol and higher cariogenic bacterial counts were each independently associated with higher dental caries risk; not pooled (ungraded).

1 finding from 1 review