Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,123 questions · 2,188 findings · 243 reviews

No studies found 493 · 22.5%GRADE not reported 160 · 7.3%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.6%High 97 · 4.4%

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

Eradication of MRSA · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen

Oral plus nebulised antibiotics showed no clear difference in eradication of MRSA compared with oral antibiotics plus nebulised placebo (low certainty).

1 finding from 1 review

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

Time until next positive MRSA isolate (from clinically relevant respiratory culture) · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics at time of replacement vs no antibiotics at time of replacement

Adverse effects (Death) · adults with replacing long‐term indwelling urinary catheters

It is very uncertain whether antibiotics at time of replacement changes adverse effects (Death) compared with no antibiotics at time of replacement (very low certainty).

1 finding from 1 review

Antibiotics vs placebo

Recurrence · sexual partners of women with bacterial vaginosis

It is very uncertain whether any antibiotic treatment changes recurrence compared with placebo (very low certainty).

2 findings from 1 review

Antibiotics vs placebo

Clinical improvement · sexual partners of women with bacterial vaginosis

Any antibiotic treatment showed no clear difference in clinical improvement compared with placebo (high certainty).

2 findings from 1 review

Antibiotics vs placebo

Symptomatic improvement · sexual partners of women with bacterial vaginosis

Any antibiotic treatment showed no clear difference in symptomatic improvement during the first week compared with placebo (high certainty).

3 findings from 1 review