Adverse effects (tooth staining and other side effects) · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
SDF commonly causes black staining of arrested lesions; only mild, transient adverse events were reported, with no major adverse events (ungraded).
1 finding from 1 review
Intervention not reported
Multifocal soft contact lenses · children with progressive myopia (26 studies, 4949 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Intervention not reported
Multifocal soft contact lenses · children with progressive myopia (36 studies, 6263 participants) in the analysis Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Intervention not reported
Multifocal soft contact lenses · children with progressive myopia (21 studies, 4169 participants in the analysis) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Intervention not reported
Multifocal soft contact lenses · children with progressive myopia (38 studies, 6525 participants in analyses) Interventions: optical and pharmacological Comparator:…
1 finding from 1 review
Healing of MRONJ (soft tissue healing) · Women with osteoporosis and established MRONJ
It is very uncertain whether concentrated growth factor (CGF) and primary wound closure changes healing of MRONJ (soft tissue healing) compared with primary wound closure only (very low certainty).
1 finding from 1 review
Intervention not reported
Bifocal vs single vision soft contact lenses · children with myopia (nearsightedness)
1 finding from 1 review
Intervention not reported
Rigid gas permeable contact lenses vs spectacles or soft contact lenses · children with myopia (nearsightedness)
1 finding from 1 review
Intervention not reported
Spherical aberration soft contact lenses vs single vision soft contact lenses · children with myopia (nearsightedness)
1 finding from 1 review
Children's SSB intake (SSB drinks/d, soft drink glasses/d and regular soda servings/d) Measured by questionnaires · children aged 4 to 14 years
1 finding from 1 review
Soft tissue pathology · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in soft tissue pathology between pulpotomy and pulpectomy (RR 3.11, 95% CI 0.54 to 17.7; ungraded).
1 finding from 1 review
RR 3.11 [0.54, 17.7]
Studies not reported
GRADE not reported
Secondary outcome: Improvement of disease activity (skin softening) · children and adults with active morphea (circumscribed morphea, linear scleroderma (with trunk/limb variant and head variant), generalised…
1 finding from 1 review
Secondary outcome: Improvement of disease activity (skin softening) · children and adults with active morphea (circumscribed morphea, linear scleroderma (with trunk/limb variant and head variant), generalised…
1 finding from 1 review
Secondary outcome: Improvement of disease activity (skin softening) · children and adults with active morphea (circumscribed morphea, linear scleroderma (with trunk/limb variant and head variant), generalised…
1 finding from 1 review
Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
It is very uncertain whether 2% mepivacaine, 1:20,000 levonordefrin changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).
1 finding from 1 review
Success of local anaesthesia (soft tissue, self-reported; 100% success in all studies) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review
'100% success' (lidocaine 1:100,000 vs 3% mepivacaine plain): infraorbital block - Berberich 2009 40/40 vs 40/40; IANB - Cohen 1993 27/27 vs 34/34, McLean 1993 30/30 vs 30/30. Both 100% successful.
3 studies · 121 participants
GRADE not reported
Success of local anaesthesia (soft tissue, self-reported; 100% success in all studies) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review
'Other comparisons with 100% success': IANB - Allegretti 2016 22/22 vs 22/22; Visconti 2016 21/21 vs 21/21. Both formulations 100% successful; no meta-analysis (no difference).
2 studies · 43 participants
GRADE not reported
Duration of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
It is very uncertain whether 4% prilocaine plain changes duration of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).
1 finding from 1 review
Speed of onset of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
It is very uncertain whether 4% articaine, 1:100,000 epinephrine changes speed of onset of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).
1 finding from 1 review
Speed of onset of anaesthesia (soft tissue, simulated) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
4% prilocaine, 1:200,000 epinephrine showed no clear difference in speed of onset of anaesthesia (soft tissue, simulated) compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).
1 finding from 1 review