Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

87 questions · 88 findings · 12 reviews

No studies found 7 · 8%GRADE not reported 4 · 4.5%Very low 35 · 39.8%Low 21 · 23.9%Moderate 17 · 19.3%High 4 · 4.5%

SSRIs or SNRIs vs amitriptyline

Participants who withdraw because of an adverse event or any other reason · patients for whom migraine preventive interventions are indicated

SSRIs or SNRIs showed no clear difference in withdrawn (for any reasons and due to adverse events) compared with amitriptyline (low certainty).

1 finding from 1 review