Anterograde amnesia (defined by number of participants who recalled the procedure) · Children requiring sedation before voiding cystourethrograms and adults undergoing MRI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Disinhibition or excitation · Children requiring sedation before voiding cystourethrograms and adults undergoing MRI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Discomfort/pain · Children requiring sedation before voiding cystourethrograms and adults undergoing MRI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Allergic or anaphylactoid reaction · Children requiring sedation before voiding cystourethrograms and adults undergoing MRI
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Anterograde amnesia (defined by number of participants who recalled the procedure) · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
Intravenous midazolam may leads to lower anterograde amnesia (defined by number of participants who recalled… compared with diazepam (low certainty).
1 finding from 1 review
Disinhibition or excitation · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Discomfort/pain · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
Intravenous midazolam showed no clear difference in discomfort/pain compared with diazepam (low certainty).
1 finding from 1 review
Allergic or anaphylactoid reaction · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Anxiety · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy
1 finding from 1 review
Side effects or other adverse events · emergency department procedural sedation
1 finding from 1 review
Participant satisfaction (as defined by study authors) · emergency department procedural sedation
1 finding from 1 review
Adverse effects: pain on injection (solution deposition), Heft-Parker VAS 0-170 mm · emergency department procedural sedation
1 finding from 1 review
Duration of mechanical ventilation · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
Risk of delirium · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes risk of delirium compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Risk of coma · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes risk of coma compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Bradycardia · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes incidence of bradycardia compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Total duration of weaning defined as study randomization to successful extubation (hours) · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
Duration of ICU stay · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
All‐cause mortality · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes mortality compared with traditional sedative agents (very low certainty).
1 finding from 1 review
ICU length of stay (general intensive care patients) · Mechanically ventilated adults in the intensive care unit
1 finding from 1 review