Cochrane · systematic review · CD007399

The use of propofol for procedural sedation in emergency departments

Wakai, A, Blackburn, C, McCabe, A, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Intravenous propofol compared with alternative intravenous sedative or hypnotic for emergency department procedural sedation

Population: emergency department procedural sedation
3 questions
OutcomeEffectEvidenceStatus / GRADE
Adverse effects (as defined by study authors)
Intravenous propofol vs alternative intravenous sedative or hypnotic
no estimate extracted7 studies · 527 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Participant satisfaction (as defined by study authors)
Intravenous propofol vs alternative intravenous sedative or hypnotic
no estimate extracted4 studies · 413 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Pain with injection
Intravenous propofol vs alternative intravenous sedative or hypnotic
no estimate extracted3 studies · 193 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias