Findings

What do systematic reviews say?

55 questions · 55 findings · 4 reviews · Pregnancy and Childbirth

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No studies found 9 · 16.4%GRADE not reported 20 · 36.4%Very low 2 · 3.6%Low 7 · 12.7%Moderate 13 · 23.6%High 4 · 7.3%

Universal screening vs case finding

Thyroid dysfunction diagnosed in pregnancy: hypothyroid · women during pregnancy

Universal screening leads to higher thyroid dysfunction diagnosed in pregnancy: hypothyroid compared with case finding (high certainty).

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
RR 3.15 [1.91, 5.2]
1 study · 4562 participants
High

Universal screening vs case finding

Thyroid dysfunction diagnosed in pregnancy: hyperthyroid · women during pregnancy

Universal screening showed no clear difference in thyroid dysfunction diagnosed in pregnancy: hyperthyroid compared with case finding (moderate certainty).

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
RR 4.5 [0.97, 20.82]
1 study · 4562 participants
Moderate

Universal screening vs case finding

Pre‐eclampsia · women during pregnancy

Universal screening showed no clear difference in pre‐eclampsia compared with case finding (moderate certainty).

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
RR 0.87 [0.64, 1.18]
1 study · 4516 participants
Moderate

Universal screening vs case finding

Neurosensory disability · women during pregnancy

The review found no eligible studies for this question.

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Universal screening vs case finding

Preterm birth · women during pregnancy

Universal screening showed no clear difference in preterm birth compared with case finding (high certainty).

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
RR 0.99 [0.8, 1.24]
1 study · 4516 participants
High

Universal screening vs case finding

Miscarriage · women during pregnancy

Universal screening showed no clear difference in miscarriage compared with case finding (moderate certainty).

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
RR 0.9 [0.68, 1.19]
1 study · 4516 participants
Moderate

Universal screening vs case finding

Adverse events associated with treatment · women during pregnancy

The review found no eligible studies for this question.

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Universal screening vs case finding

Fetal or neonatal mortality · women during pregnancy

Universal screening showed no clear difference in fetal and neonatal death compared with case finding (moderate certainty).

1 finding from 1 review

Screening and subsequent management for thyroid dysfunction pre‐pregnancy and during pregnancy for improving maternal… 2015 · Cochrane Headline outcomes only
RR 0.92 [0.42, 2.02]
1 study · 4516 participants
Moderate

AFI vs SDVP: summary of findings table

Admission to neonatal intensive care unit · pregnant women to prevent adverse pregnancy outcome

AFI showed no clear difference in admission to neonatal intensive care unit compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 1.04 [0.85, 1.26]
5 studies · 3226 participants
Moderate

AFI vs SDVP: summary of findings table

Any perinatal death after randomisation · pregnant women to prevent adverse pregnancy outcome

The review found no eligible studies for this question.

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

AFI vs SDVP: summary of findings table

Umbilical artery pH < 7.1 · pregnant women to prevent adverse pregnancy outcome

AFI showed no clear difference in umbilical artery pH less than 7.1 compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 1.1 [0.74, 1.65]
3 studies · 2625 participants
Moderate

AFI vs SDVP: summary of findings table

Rate of diagnosis of oligohydramnios · pregnant women to prevent adverse pregnancy outcome

AFI probably leads to higher rate of diagnosis of oligohydramnios compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 2.39 [1.73, 3.28]
5 studies · 3226 participants
Moderate

AFI vs SDVP: summary of findings table

Caesarean section · pregnant women to prevent adverse pregnancy outcome

AFI showed no clear difference in caesarean delivery compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 1.09 [0.92, 1.29]
5 studies · 3226 participants
Moderate

AFI vs SDVP: summary of findings table

Rate of induction of labor · pregnant women to prevent adverse pregnancy outcome

AFI leads to higher rate of induction of labor compared with SDVP: summary of findings table (high certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 1.92 [1.5, 2.46]
4 studies · 2138 participants
High

AFI vs SDVP: summary of findings table

Caesarean delivery for fetal distress · pregnant women to prevent adverse pregnancy outcome

AFI probably leads to higher caesarean delivery for fetal distress compared with SDVP: summary of findings table (moderate certainty).

1 finding from 1 review

Amniotic fluid index versus single deepest vertical pocket as a screening test for preventing adverse pregnancy outcome 2008 · Cochrane Headline outcomes only
RR 1.46 [1.08, 1.96]
5 studies · 3226 participants
Moderate