Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

115 questions · 119 findings · 21 reviews · Headline outcomes only

No studies found 24 · 20.2%GRADE not reported 3 · 2.5%Very low 43 · 36.1%Low 30 · 25.2%Moderate 14 · 11.8%High 5 · 4.2%

Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage)

Transfusion‐related acute lung injury ‐ not measured · patients requiring blood transfusion (children with malaria and adults with a traumatic injury)

The review found no eligible studies for this question.

1 finding from 1 review

IV or oral iron alone vs no treatment

Red blood cell transfusions (Subnet based on 69 studies including 18,684 participants) · patients at any age with solid cancer or haematological malignancy

IV or oral iron alone showed no clear difference in red blood cell transfusions (Subnet based on 69 studies including… compared with no treatment (low certainty).

1 finding from 1 review

ESA with or without iron vs no treatment

Red blood cell transfusions (Subnet based on 69 studies including 18,684 participants) · patients at any age with solid cancer or haematological malignancy

ESA with or without iron probably leads to lower red blood cell transfusions (Subnet based on 69 studies including… compared with no treatment (moderate certainty).

1 finding from 1 review

Intervention not reported

Use of 1 or more red blood cell transfusions (low and high doses of EPO) · preterm infants with low birth weight

The intervention may leads to lower use of 1 or more red blood cell transfusions (low and high doses of… (low certainty).

1 finding from 1 review

Intervention not reported

Participants receiving red blood cell transfusions · patients with cancer

The intervention probably leads to lower participants receiving red blood cell transfusions (moderate certainty).

1 finding from 1 review

Intervention vs control

Blood transfusion (red cell or whole blood) · Patients with liver transplantation.
5 findings from 1 review
Show 2 more findings

Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)

Blood transfusion (red cell or whole blood) · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…

It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes blood transfusion (red cell or whole blood) compared with normal care (misoprostol) (very low certainty).

1 finding from 1 review

Bakri balloon tamponade vs condom‐loaded Foley Catheter (one intrauterine tamponade compared to another intrauterine tamponade technique)

Blood transfusion (red cell or whole blood) · women with primary atonic postpartum haemorrhage following vaginal delivery

It is very uncertain whether bakri balloon tamponade changes blood transfusion (red cell or whole blood) compared with condom‐loaded Foley Catheter (one intrauterine tamponade compared to… (very low certainty).

1 finding from 1 review

External uterine compression (all methods) plus normal care vs normal care

Blood transfusion (red cell or whole blood) · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

It is very uncertain whether external uterine compression (all methods) plus normal care changes blood transfusion (red cell or whole blood) compared with normal care (very low certainty).

1 finding from 1 review

One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)

Blood transfusion (red cell or whole blood) · treating primary postpartum haemorrhage

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Blood transfusion (red cell or whole blood) · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

The review found no eligible studies for this question.

1 finding from 1 review