Cochrane · systematic review · CD009330
Prolonged storage of packed red blood cells for blood transfusion
Martí‐Carvajal, AJ, Simancas‐Racines, D, Peña‐González, BS · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
InjuriesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Long‐stored ('older') PRBC (≥ 21 days of storage) compared with short‐stored (fresh) PRBC (< 21 days of storage) for patients requiring blood transfusion
Population: patients requiring blood transfusion (children with malaria and adults with a traumatic injury)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death from any cause Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | RR 2.36 [0.65, 8.52] | 2 studies · 91 participants | Very low Downgraded: imprecision |
Transfusion‐related acute lung injury ‐ not measured Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | no estimate extracted | NR | No studies |
Postoperative infections ‐ not measured Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | no estimate extracted | NR | No studies |
Post‐injury coagulopathy ‐ not measured Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | no estimate extracted | NR | No studies |
Multiple organ failure post‐injury ‐ not measured Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | no estimate extracted | NR | No studies |
Adverse event (Hyperkalaemia) ‐ not measured Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | no estimate extracted | NR | No studies |
Adverse event (Metabolic acidosis) Long‐stored ('older') PRBC (≥ 21 days of storage) vs short‐stored (fresh) PRBC (< 21 days of storage) | no estimate extracted | 1 study · 22 participants | Very low Downgraded: risk of bias, imprecision |