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Evidence found and GRADE certainty

135 questions · 156 findings · 30 reviews · All outcomes

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No studies found 66 · 42.3%GRADE not reported 61 · 39.1%Very low 15 · 9.6%Low 13 · 8.3%Moderate 0 · 0%High 1 · 0.6%

External control of fluoride concentration vs Not applicable

Water samples with fluoride concentration below the acceptable range · Brazilian cities in the Southeast region with artificially fluoridated public water supplies

In the Southeast region, 24.6% of samples were below the acceptable range.

1 finding from 1 review

Rubber dam vs Isolite system

Participant acceptance/satisfaction · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)
1 finding from 1 review
  • Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
    Pit and fissure sealing (permanent molars)
    Rubber dam may be associated with significantly lower satisfaction than the Isolite system but evidence very uncertain, mainly worse comfort (31%, P=0.02) and less preference (26%, P=0.002) (Alhareky 2014).
    1 study · 42 participants
    Very low

External control of fluoride concentration vs Not applicable

Water samples with fluoride concentration above the acceptable range · Brazilian cities in the Northeast region with artificially fluoridated public water supplies

In the Northeast region, 0.2% of samples were above the acceptable range.

1 finding from 1 review

Rubber dam isolation and moisture control (alone or with saliva aspiration) vs Cotton rolls (with or without saliva aspiration)

Participant acceptance/satisfaction · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)
1 finding from 1 review
  • Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
    Non-carious cervical lesions (composite restoration)
    Evidence did not support higher acceptance/preference for rubber dam than cotton rolls (P = 0.85 from binomial test on 28 participants; very low-certainty evidence) (Loguercio 2015).
    1 study · 28 participants
    Very low

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Acceptability and feasibility of the intervention to patients and dentists · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Hinokitiol gel vs Placebo gel

VSC: methyl mercaptan · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Hinokitiol gel showed no clear difference in VSC: methyl mercaptan compared with placebo gel; GRADE not reported.

1 finding from 1 review

Chlorine dioxide mouthrinse (with tongue scraping) vs Chlorhexidine mouthwash (with tongue scraping)

VSC: methyl mercaptan · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Chlorine dioxide mouthrinse (with tongue scraping) showed no clear difference in VSC: methyl mercaptan compared with chlorhexidine mouthwash (with tongue scraping); GRADE not reported.

1 finding from 1 review

Benzethonium chloride mouthwash vs Placebo mouthwash

VSC: methyl mercaptan · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Benzethonium chloride mouthwash showed no clear difference in VSC: methyl mercaptan compared with placebo mouthwash; GRADE not reported.

1 finding from 1 review

Laser enamel preparation alone (Er,Cr:YSGG or CO2 laser) vs Acid-etching (phosphoric acid)

Acceptability · Caries-free children to young adults with premolars/molars requiring pit-and-fissure sealants

Both laser and acid-etching preparation were well accepted by patients (VAS, P = 1.000; ungraded, single study).

1 finding from 1 review

Pycnogenol chewing gum vs Placebo chewing gum

VSC: methyl mercaptan · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

Pycnogenol chewing gum showed no clear difference in VSC: methyl mercaptan compared with placebo chewing gum; GRADE not reported.

1 finding from 1 review

Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite

Marginal adaptation (clinically detectable deterioration) · People with permanent posterior teeth restored with class I or II direct restorations

At 60 months, marginal adaptation did not differ significantly between the composites (4 groups; ungraded).

5 findings from 1 review
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5.3% HP strip vs 5% HP gel in tray

Patient comfort / acceptability · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 5.3% HP strip changes patient comfort / acceptability compared with 5% HP gel in tray (very low certainty).

1 finding from 1 review

Altered-cast impression technique (ACIP), polyether vs One-piece cast technique (OPC), polyether

Denture base adaptation (buccal shelf and ridge crest) · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture

Altered-cast impression technique (ACIP), polyether led to lower denture base adaptation (buccal shelf and ridge crest) compared with one-piece cast technique (OPC), polyether; GRADE not reported.

1 finding from 1 review

Fluoride mouthrinse (any fluoride agent, concentration, volume, frequency or technique; swished and expectorated, not swallowed) vs placebo or no treatment

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

It is very uncertain whether fluoride mouthrinse (any fluoride agent, concentration, volume,… changes unacceptability of treatment as measured by leaving study early… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs placebo or no treatment

Unacceptability of treatment (dropouts/exclusions during the trial) · Children and adolescents aged 16 years or less

Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in unacceptability of treatment (dropouts/exclusions during the trial) compared with placebo or no treatment; GRADE not reported.

3 findings from 1 review

Micro-invasive treatment (proximal sealing or resin infiltration): resin sealant, glass ionomer sealant, polyurethane/adhesive patch, or resin infiltration vs Non-invasive / control treatment

Material deficiency (retention/adaptation loss; re-treatment) · Dentate children and adults with non-cavitated proximal caries lesions extending into enamel or dentine (not pulp) in primary or permanent…
1 finding from 1 review

Surgical anchorage (mini-screw or mid-palatal implant) vs Conventional anchorage (headgear, transpalatal/palatal arch, etc.)

Acceptability · Patients of any age undergoing orthodontic treatment with fixed appliances and requiring anchorage (adolescents to adults up to 48-54 years)
1 finding from 1 review