Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

164 questions · 165 findings · 15 reviews · Skin

No studies found 50 · 30.3%GRADE not reported 14 · 8.5%Very low 27 · 16.4%Low 37 · 22.4%Moderate 31 · 18.8%High 6 · 3.6%

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyloestradiol and norgestrel

Number of participants reporting non‐serious adverse effects · participants with hidradenitis suppurativa

Ethinyloestradiol and cyproterone acetate probably leads to lower number of participants reporting non‐serious adverse effects compared with ethinyloestradiol and norgestrel (moderate certainty).

1 finding from 1 review

Thermotherapy one session (at 50 ºC for 30 seconds) vs meglumine antimoniate (20 mg Sb5/kg/day

Complete cure, at least 3 months after the end of treatment · People with American cutaneous leishmaniasis

Thermotherapy one session (at 50 ºC for 30 seconds) leads to lower complete cure, at least 3 months after the end of treatment compared with meglumine antimoniate (20 mg Sb5/kg/day (high certainty).

1 finding from 1 review

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether triamcinolone acetonide 0.1% cream with occlusive dressing changes proportion of participants cleared or almost cleared ‐ compared with clobetasol cream 0.05% cream (very low certainty).

1 finding from 1 review