Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

107 questions · 107 findings · 25 reviews · Eyes and Vision

No studies found 35 · 32.7%GRADE not reported 1 · 0.9%Very low 17 · 15.9%Low 25 · 23.4%Moderate 27 · 25.2%High 2 · 1.9%

Phaco‐AIT vs Phaco‐Trab

Proportion of participants who were medication‐free (not using drops) at 12 months · people with open‐angle glaucoma

It is very uncertain whether phaco‐AIT changes proportion of participants who were medication‐free (not using… compared with phaco‐Trab (very low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in daily IOP‐lowering medicationsat 24 months… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Combined trabeculotomy with trabeculectomy vs trabeculotomy

Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma

It is very uncertain whether combined trabeculotomy with trabeculectomy changes surgical success: proportion with postoperative IOP ≤ 21 mmHg with… compared with trabeculotomy (very low certainty).

1 finding from 1 review

Viscotrabeculotomy vs conventional trabeculotomy

Proportion with postoperative IOP ≤ 21 mmHg (surgical success) with or without glaucoma medications 6 months after surgery · children at or before five years of age with primary congenital glaucoma

It is very uncertain whether viscotrabeculotomy changes proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (very low certainty).

1 finding from 1 review

Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy

Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma

Microcatheter‐assisted trabeculotomy probably leads to higher proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (moderate certainty).

1 finding from 1 review

Intervention not reported

Mean number of glaucoma medications 12 months postintervention · adults with refractory glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Mean number of glaucoma medications 12 months postintervention · adults with refractory glaucoma
1 finding from 1 review

Ahmed implant vs Baerveldt implant

Mean number of antiglaucoma medications at 1‐year · People with glaucoma

Ahmed implant probably leads to higher mean number of antiglaucoma medications at 1‐year compared with baerveldt implant (moderate certainty).

1 finding from 1 review

Ahmed implant vs Molteno implant

Mean number of antiglaucoma medications at 1‐year · People with glaucoma

Ahmed implant showed no clear difference in mean number of antiglaucoma medications at 1‐year compared with molteno implant (low certainty).

1 finding from 1 review

Molteno implant vs Schocket shunt

Mean number of antiglaucoma medications at 1‐year · People with glaucoma

The review found no eligible studies for this question.

1 finding from 1 review