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Evidence found and GRADE certainty

150 questions · 154 findings · 22 reviews · Eyes and Vision

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No studies found 6 · 3.9%GRADE not reported 3 · 1.9%Very low 44 · 28.6%Low 50 · 32.5%Moderate 48 · 31.2%High 3 · 1.9%

Intervention not reported

Change in metamorphopsia from baseline to 6‐month · People with lamellar macular holes

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Systemic 7‐methylxanthine vs placebo · children with myopia (nearsightedness)
1 finding from 1 review

Spectacle correction vs no spectacles

Proportion of children without refractive error in the emmetropization range at 3 years · infants or children with hyperopia

It is very uncertain whether spectacle correction changes proportion of children without refractive error in the… compared with no spectacles (very low certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry short‐term · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review

Antibiotics vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

Antibiotic showed no clear difference in ocular C trachomatis infection Positive test for C trachomatis… compared with control (low certainty).

1 finding from 1 review

Neuroprotection vs control

Vertical cup‐disc ratio: the proportion of participants with asymmetrical vertical cup‐disc ratio greater than 0.3 at 4 years' · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Progression (increase in maximal keratometry of 1.5 dioptres or more) · people with keratoconus

It is very uncertain whether the intervention changes progression (increase in maximal keratometry of 1.5 dioptres or more) (very low certainty).

1 finding from 1 review

Intervention not reported

Steepness of the cornea (maximal keratometry) (measured using dioptres. A higher dioptre represents steeper cornea and worse outcome) · people with keratoconus
1 finding from 1 review

Intervention not reported

Failed graft Including cases where the DALK or PK procedure was unable to be successfully completed as outlined in the methodology for the study. As at, at least 3 months post‐suture removal · Patients with keratoconus undergoing corneal grafting

It is very uncertain whether the intervention changes failed graft Including cases where the DALK or PK procedure was… (very low certainty).

1 finding from 1 review

Intervention not reported

Failed graft Including cases where the DALK or PK procedure was unable to be successfully completed as outlined in the methodology for the study · Patients with keratoconus undergoing corneal grafting

The intervention led to higher failed graft Including cases where the DALK or PK procedure was…; GRADE not reported.

1 finding from 1 review