Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

74 questions · 77 findings · 16 reviews · Pregnancy and Childbirth

No studies found 3 · 3.9%GRADE not reported 9 · 11.7%Very low 19 · 24.7%Low 25 · 32.5%Moderate 13 · 16.9%High 8 · 10.4%

Case notes vs control

Epidural analgesia during labour · pregnant women from the time of their first antenatal visit to the end of the puerperium

Case notes showed no clear difference in epidural analgesia used in labour compared with control (low certainty).

1 finding from 1 review

Upright position vs recumbent position

Operative birth (caesarean or instrumental vaginal) · women in the second stage of labour with epidural anaesthesia

Upright position leads to higher operative birth (caesarean or instrumental vaginal) compared with recumbent position (sensitivity analyses ‐ studies at low risk of… (high certainty).

2 findings from 1 review

Upright position vs recumbent position

Caesarean section · women in the second stage of labour with epidural anaesthesia

Upright position leads to higher caesarean section compared with recumbent position (sensitivity analyses ‐ studies at low risk of… (high certainty).

2 findings from 1 review

Upright position vs recumbent position

Instrumental vaginal birth · women in the second stage of labour with epidural anaesthesia

Upright position showed no clear difference in instrumental vaginal birth compared with recumbent position (sensitivity analyses ‐ studies at low risk of… (low certainty).

2 findings from 1 review

Upright position vs recumbent position

Blood loss (greater than 500 mL) (trial authors defined it as PPH requiring blood transfusion) · women in the second stage of labour with epidural anaesthesia

Upright position showed no clear difference in blood loss (greater than 500 mL) (trial authors defined it as PPH… compared with recumbent position (moderate certainty).

1 finding from 1 review

Upright position vs recumbent position

Abnormal fetal heart rate patterns, requiring intervention · women in the second stage of labour with epidural anaesthesia

It is very uncertain whether upright position changes abnormal fetal heart rate patterns, requiring intervention compared with recumbent position (very low certainty).

1 finding from 1 review