Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

423 questions · 477 findings · 107 reviews

No studies found 44 · 9.2%GRADE not reported 97 · 20.3%Very low 165 · 34.6%Low 113 · 23.7%Moderate 41 · 8.6%High 17 · 3.6%

Imiquimod vs MAL‐PDT

Early treatment failure · adults with basal cell carcinoma of the skin

Imiquimod cream showed no clear difference in early treatment failure compared with MAL‐PDT (moderate certainty).

1 finding from 1 review

Early discharge vs non‐early discharge

Treatment failure; rehospitalization or adjustment of antimicrobial treatment (or both) in number of episodes · children with cancer

Early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with non‐early discharge (low certainty).

1 finding from 1 review

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

All‐cause mortality · febrile neutropenia

Early discontinuation of antibiotic treatment showed no clear difference in mortality compared with treatment until neutropenia resolution (low certainty).

1 finding from 1 review

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

Clinical failure · febrile neutropenia

It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).

1 finding from 1 review

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

Bacteraemia · febrile neutropenia

It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).

1 finding from 1 review

Early warning signs training and treatment as usual vs treatment

Clinical response: mental state ‐ relapse ‐ medium term Relapse rate · patients with schizophrenia

It is very uncertain whether early warning signs training and treatment as usual changes relapse: Rate of relapse compared with treatment (very low certainty).

1 finding from 1 review

Early warning signs training and treatment as usual vs treatment

Service use: Time to re‐hospitalisation · patients with schizophrenia

It is very uncertain whether early warning signs training and treatment as usual changes service use: Time to re‐hospitalisation compared with treatment (very low certainty).

1 finding from 1 review