Doxycycline vs tetracycline
Time to defervescence · adults with scrub typhus
1 finding from 1 review
- no estimate extracted1 study · 116 participantsLow
Findings
What do systematic reviews say?
173 questions · 174 findings · 12 reviews · Headline outcomes only
No studies found 34 · 19.5%GRADE not reported 26 · 14.9%Very low 34 · 19.5%Low 40 · 23%Moderate 25 · 14.4%High 15 · 8.6%
Doxycycline vs tetracycline
Serious adverse events · adults with scrub typhus
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Doxycycline vs quinolones
Duration of diarrhoea · Adults and children with cholera diarrhoea
1 finding from 1 review
- no estimate extracted3 studies · 126 participantsLow
Doxycycline vs quinolones
Stool volume · Adults and children with cholera diarrhoea
1 finding from 1 review
- no estimate extracted4 studies · 435 participantsLow
Doxycycline vs quinolones
Bacteriological failure · Adults and children with cholera diarrhoea
Doxycycline may leads to higher bacteriological failure compared with quinolones (low certainty).
1 finding from 1 review
- RR 5.84 [2.7, 12.65]4 studies · 386 participantsLow
Doxycycline+Rifampicin vs Doxycycline+Streptomycin
total treatment failure · patients with human Brucellosis
Doxycycline+Rifampicin probably leads to higher total treatment failure compared with doxycycline+Streptomycin (moderate certainty).
1 finding from 1 review
- RR 1.91 [1.07, 3.42]7 studies · 567 participantsModerate
Doxycycline+Rifampicin vs Doxycycline+Streptomycin
Minor adverse drug reactions · patients with human Brucellosis
Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with doxycycline+Streptomycin (low certainty).
1 finding from 1 review
- RR 1.38 [0.99, 1.92]5 studies · 473 participantsLow
Doxycycline+Streptomycin vs Doxycycline+Gentamycin
total treatment failure · patients with human Brucellosis
Doxycycline+Streptomycin showed no clear difference in total treatment failure compared with doxycycline+Gentamycin (low certainty).
1 finding from 1 review
- OR 1.85 [0.84, 4.08]2 studies · 345 participantsLow
Doxycycline+Streptomycin vs Doxycycline+Gentamycin
Minor adverse drug reactions · patients with human Brucellosis
It is very uncertain whether doxycycline+Streptomycin changes minor adverse drug reactions compared with doxycycline+Gentamycin (very low certainty).
1 finding from 1 review
- RR 0.85 [0.6, 1.22]2 studies · 345 participantsVery low
Doxycycline+Rifampicin vs Quinolones+Rifampicin
total treatment failure · patients with human Brucellosis
Doxycycline+Rifampicin showed no clear difference in total treatment failure compared with quinolones+Rifampicin (moderate certainty).
1 finding from 1 review
- OR 0.94 [0.45, 1.98]3 studies · 181 participantsModerate
Doxycycline+Rifampicin vs Quinolones+Rifampicin
Minor adverse drug reactions · patients with human Brucellosis
Doxycycline+Rifampicin showed no clear difference in minor adverse drug reactions compared with quinolones+Rifampicin (low certainty).
1 finding from 1 review
- RR 1.8 [0.78, 4.18]4 studies · 296 participantsLow
Intervention not reported
Doxycycline (4 RCTs; 308 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
- Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 308 participantsLow
Intervention not reported
Doxycycline (4 RCTs, 308 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
- Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 308 participantsLow
Intervention not reported
Doxycycline · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Doxycycline (1 RCT, 80 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
- Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 80 participantsVery low
Intervention not reported
Doxycycline · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Doxycycline (5 RCTs, 117 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
- Interventions for the management of malignant pleural effusions: a network meta‐analysis 2020 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 117 participantsLow
Antibiotics vs other antibiotics
Adverse events considered non‐serious (penicillin versus doxycycline) · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus doxycycline) compared with other antibiotics (very low certainty).
1 finding from 1 review
- RR 2.8 [0.12, 67.66]1 study · 168 participantsVery low
Antibiotics vs other antibiotics
All‐cause mortality (penicillin versus doxycycline) · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (penicillin versus doxycycline) compared with other antibiotics (very low certainty).
1 finding from 1 review
- RR 0.93 [0.13, 6.46]1 study · 168 participantsVery low
Antibiotics vs other antibiotics
All‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) compared with other antibiotics (very low certainty).
1 finding from 1 review
- RR 0.18 [0.01, 3.78]1 study · 169 participantsVery low