Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

518 questions · 558 findings · 63 reviews

No studies found 77 · 13.8%GRADE not reported 143 · 25.6%Very low 89 · 15.9%Low 137 · 24.6%Moderate 95 · 17%High 17 · 3%

Calcium supplementation/fortification vs placebo or no intervention

Low birthweight · healthy pregnant women receiving calcium supplementation vs placebo or no treatment

Calcium supplementation showed no clear difference in low birthweight (< 2500 g) compared with placebo or no treatment (maternal outcomes) (moderate certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo or control

Persons with hypercalcaemia ‐ Vitamin D (D2, D3 or 25(OH)D) plus calcium (1 year estimate) · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium showed no clear difference in persons with hypercalcaemia ‐ Vitamin D (D2, D3 or 25(OH)D) plus… compared with control or placebo (low certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo or control

Persons with renal disease (calculi or insufficiency) ‐ Vitamin D (D2, D3 or 25(OH)D) plus calcium (1 year estimate) · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium leads to higher persons with renal disease (calculi or insufficiency) ‐ Vitamin D… compared with control or placebo (high certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo or control

Deaths ‐ Vitamin D (D2, D3, 25(OH)D) plus calcium (1 year estimate) · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium showed no clear difference in deaths ‐ Vitamin D (D2, D3, 25(OH)D) plus calcium (1 year estimate) compared with control or placebo (high certainty).

1 finding from 1 review

Hydraulic calcium silicate cements (HCSC; MTA or Biodentine) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…

At 36-month follow-up, HCSC show higher odds of clinical and radiographic success than CaOH (OR 2.34, 95% CI 1.43 to 3.84; ungraded subgroup).

3 findings from 1 review

Calcium antagonists vs placebo

Death or dependency at end of · people with acute ischemic stroke

Calcium antagonists showed no clear difference in death or dependency at end of compared with placebo (moderate certainty).

1 finding from 1 review

Calcium antagonists vs placebo

Death at the end of treatment · people with acute ischemic stroke

Calcium antagonists showed no clear difference in death at the end of treatment compared with placebo (moderate certainty).

1 finding from 1 review

Calcium antagonists vs placebo

Recurrence of stroke at the end of · people with acute ischemic stroke

Calcium antagonists showed no clear difference in recurrence of stroke at the end of compared with placebo (moderate certainty).

1 finding from 1 review

Calcium antagonists vs placebo

Adverse events during treatment period · people with acute ischemic stroke

Calcium antagonists showed no clear difference in adverse events during treatment period compared with placebo (moderate certainty).

1 finding from 1 review

Calcium antagonists vs placebo

Systolic blood pressure · people with acute ischemic stroke

Calcium antagonists showed no clear difference in mean systolic blood pressure during or at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Calcium hydroxide cement (Dycal) vs Calcium sulphate hemihydrate (DentoGen)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether calcium hydroxide cement (Dycal) changes radiological failure compared with calcium sulphate hemihydrate (DentoGen) (very low certainty).

1 finding from 1 review