Recurrence of pneumonia ‐ NF‐GNB · hospital‐acquired pneumonia
Should short‐course antibiotic therapy probably leads to higher recurrence of pneumonia NF‐GNB Clinical and/or microbiological… compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Recurrence of pneumonia ‐ MRSA · hospital‐acquired pneumonia
Should short‐course antibiotic therapy showed no clear difference in recurrence of pneumonia MRSA Clinical and/or microbiological criteria compared with prolonged‐course antibiotic therapy be used (moderate certainty).
1 finding from 1 review
Clinical outcomes · respiratory infections
1 finding from 1 review
Duration of clinical outcomes (pain, malaise, fever) · respiratory infections
1 finding from 1 review
Clinical outcomes: pain, malaise, fever · respiratory infections
1 finding from 1 review
Duration of clinical outcomes (pain, malaise, fever) · respiratory infections
1 finding from 1 review
Clinical cure · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in clinical cure (symptomatic and clinical recovery by the end of… compared with placebo compared to placebo (moderate certainty).
1 finding from 1 review
Treatment failure (development of more severe signs and symptoms by the end of treatment) · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy may leads to lower treatment failure (development of more severe signs and symptoms by… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
Relapse · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in relapse (children who were 'cured' but developed symptoms within… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
Pain ‐ Pain at 11 to 14 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 11 to 14 days compared with expectant observation (low certainty).
1 finding from 1 review
Vomiting, diarrhoea or rash · children with acute otitis media
Immediate antibiotics leads to higher vomiting, diarrhoea or rash compared with expectant observation (high certainty).
1 finding from 1 review
Abnormal tympanometry ‐ 1 month · children with acute otitis media
Immediate antibiotics showed no clear difference in abnormal tympanometry at 4 weeks compared with expectant observation (moderate certainty).
1 finding from 1 review
Pain ‐ pain at 2 to 3 days · children with acute otitis media
Immediate antibiotics may leads to lower pain ‐ Pain at 2 to 3 days compared with expectant observation (low certainty).
1 finding from 1 review
Pain ‐ Pain at 3 to 7 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 3 to 7 days compared with expectant observation (moderate certainty).
1 finding from 1 review
Number of participants given an antibiotic prescription within 28 days · patients with sore throat
1 finding from 1 review
Number of participants with an antibiotic dispensed · patients with sore throat
1 finding from 1 review
Antibiotics prescribed or dispensed (6 weeks or less) · antibiotic use in acute respiratory infections
Shared decision making probably leads to lower antibiotics prescribed or dispensed (6 weeks or less) compared with usual care (moderate certainty).
1 finding from 1 review
Antibiotics prescribed or dispensed (12 months or greater) · antibiotic use in acute respiratory infections
Shared decision making showed no clear difference in antibiotics prescribed or dispensed (12 months or greater) compared with usual care (low certainty).
1 finding from 1 review
Deaths · any indication
Other adverse events in people taking macrolide antibiotics showed no clear difference in deaths compared with placebo (low certainty).
1 finding from 1 review
Cardiac disorders · any indication
It is very uncertain whether other adverse events in people taking macrolide antibiotics changes cardiac disorders compared with placebo (very low certainty).
1 finding from 1 review