Findings

What do systematic reviews say?

174 questions · 184 findings · 13 reviews · Pain, Palliative and Supportive Care

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No studies found 61 · 33.2%GRADE not reported 23 · 12.5%Very low 57 · 31%Low 33 · 17.9%Moderate 10 · 5.4%High 0 · 0%

Ibuprofen vs ketorolac

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

1 finding from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low

Ibuprofen vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · children with acute postoperative pain

2 findings from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 259 participants
Moderate
Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 345 participants
Low

Ibuprofen vs placebo

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

Ibuprofen showed no clear difference in adverse events (reported in the first 7 days after the procedure) compared with placebo (low certainty).

1 finding from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
RR 0.79 [0.51, 1.23]
5 studies · 384 participants
Low

Ibuprofen vs paracetamol

Relief of pain · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medically assisted hydration vs placebo

QoL · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
Very low

Medically assisted hydration vs placebo

Survival Log‐rank analysis Study enrolment to last date of · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
Very low

Medically assisted hydration vs placebo

Adverse events NRS (scale from 0 to 10; lower score = less toxicity) · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Very low

Medically assisted hydration vs usual care

Quality of life · adults aged 18 years and older receiving palliative care

The review found no eligible studies for this question.

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medically assisted hydration vs usual care

Survival Cox regression model Study enrolment to last date of · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 200 participants
Very low

Medically assisted hydration vs usual care

Adverse events Participant events · adults aged 18 years and older receiving palliative care

1 finding from 1 review

Medically assisted hydration for adults receiving palliative care 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 242 participants
Very low

Intervention not reported

Pain intensity measured on CHQ (0‐100; 0 = worse pain), and VAS (0 to 100; 0 = no pain) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 118 participants
Very low

Intervention not reported

Depression none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Anxiety none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pain intensity none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Disability none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse events none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Depression none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Anxiety none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life none of the studies reported on this outcome · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain

The review found no eligible studies for this question.

1 finding from 1 review

Physical activity and education about physical activity for chronic musculoskeletal pain in children and adolescents 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found