Summary of Findings Table ‐ Vitamin D showed no clear difference in worsening of clinical status compared with placebo or standard care alone (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether summary of Findings Table ‐ Vitamin D changes adverse events (any grade) compared with placebo or standard care alone (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
A dose of vitamin D 4000 IU/d or more showed no clear difference in pre‐eclampsia compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
A dose of vitamin D 4000 IU/d or more showed no clear difference in gestational diabetes compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
A dose of vitamin D 4000 IU/d or more showed no clear difference in preterm birth compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
A dose of vitamin D 4000 IU/d or more showed no clear difference in low birthweight compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
Meta-analysis of randomised trials of vitamin D supplementation for Risk of hypercalcaemia: RR 3.80 (95% CI 0.90 to 16.12), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Subperiosteal erosions: RR 0.41 (95% CI 0.07 to 2.38), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Mortality: RR 1.40 (95% CI 0.38 to 5.15), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Creatinine clearance: WMD -1.68 (95% CI -6.92 to 3.56), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Risk of hyperphosphataemia: RR 1.57 (95% CI 0.97 to 2.54), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Fractures: RR 1.00 (95% CI 0.06 to 15.41), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
Meta-analysis of randomised trials of vitamin D supplementation for Risk of hypercalcaemia: RR 3.04 (95% CI 1.17 to 7.90), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
Meta-analysis of randomised trials of vitamin D supplementation for Parathyroid hormone: WMD -196.05 (95% CI -298.43 to -93.66), statistically significant. Umbrella review outcome-level evidence grade: Probable.
Meta-analysis of randomised trials of vitamin D supplementation for Risk of requiring dialysis: RR 0.76 (95% CI 0.36 to 1.62), not statistically significant. Umbrella review outcome-level evidence grade: No conclusion.