Question · asked by 1 review

A dose of vitamin D 4000 IU/d or more vs 3999 IU/d or less alone or with any other nutrient: Pre‐eclampsia

Population
women during pregnancy
Intervention
A dose of vitamin D 4000 IU/d or more
Comparison
3999 IU/d or less alone or with any other nutrient
Outcome
Pre‐eclampsia

A dose of vitamin D 4000 IU/d or more showed no clear difference in pre‐eclampsia compared with 3999 IU/d or less alone or with any other nutrient (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
A dose of vitamin D 4000 IU/d or more vs 3999 IU/d or less alone or with any other nutrient
Pre‐eclampsia · women during pregnancy
A dose of vitamin D 4000 IU/d or more showed no clear difference in pre‐eclampsia compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
Regimens of vitamin D supplementation for women during pregnancy (2019) · Cochrane Headline outcomes only
RR 0.87 [0.62, 1.22]4 studies · 1903 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Regimens of vitamin D supplementation for women during pregnancy
2019 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.