Methotrexate · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes methotrexate compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.84 [0.58, 1.22]
Studies not reported
Very low
5‐fluorouracil · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes 5‐fluorouracil compared with safe handling alone (very low certainty).
1 finding from 1 review
RR 0.63 [0.42, 0.94]
Studies not reported
Very low
Intervention not reported
Dental caries (presence; primary or permanent dentition)
The intervention led to higher dental caries (presence; primary or permanent dentition); GRADE not reported.
1 finding from 1 review
OR 1.50 [1.36, 1.64]
21 studies
GRADE not reported
Intervention not reported
Cardiovascular health · Smokers and nonsmokers
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intervention not reported
Respiratory health · Smokers and nonsmokers
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Perinatal health · Smokers and nonsmokers
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Mortality · Smokers and nonsmokers
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intervention not reported
Active smoking, hospital setting · Smokers
The intervention may leads to lower active smoking, hospital setting (low certainty).
1 finding from 1 review
Intervention not reported
Active smoking, university setting · Smokers
The intervention may leads to lower active smoking, university setting (low certainty).
1 finding from 1 review
Intervention not reported
Active smoking, prison setting · Smokers
The intervention showed no clear difference in active smoking, prison setting (low certainty).
1 finding from 1 review
Intervention not reported
Smoking‐related mortality ‐ prison setting · Smokers
1 finding from 1 review
Rubella cases Initial meta‐analysis ‐ clinical diagnosis or serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella
Gamma‐globulin probably leads to lower rubella cases Initial meta‐analysis ‐ clinical diagnosis or serology… compared with control (saline or no treatment) (moderate certainty).
1 finding from 1 review
Subgroup: rubella cases Estimated dose 0.027 to 0.037 ml/lb11 Clinical diagnosis by 2 physicians · susceptible people exposed to rubella
Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.027 to 0.037 ml/lb11… compared with control (saline or no treatment) (low certainty).
1 finding from 1 review
Subgroup: rubella cases Estimated dose 0.1 to 0.15 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella
Gamma‐globulin leads to lower subgroup: rubella cases Estimated dose 0.1 to 0.15 ml/lb11 Serology… compared with control (saline or no treatment) (high certainty).
1 finding from 1 review
Subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella
Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology… compared with control (saline or no treatment) (moderate certainty).
1 finding from 1 review
Cases of congenital rubella infection ‐ not measured · susceptible people exposed to rubella
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cases of congenital rubella syndrome ‐ not measured · susceptible people exposed to rubella
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events ‐ not measured · susceptible people exposed to rubella
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Muscle pain at rest · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)
It is very uncertain whether summary of findings: whole‐body cryotherapy (WBC) changes muscle soreness: pain at rest (VAS) compared with control (no WBC or passive rest) (very low certainty).
4 findings from 1 review
no estimate extracted
2 studies · 20 participants
Very low
no estimate extracted
3 studies · 38 participants
Very low
no estimate extracted
3 studies · 38 participants
Very low
Show 1 more finding
Tiredness · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)
1 finding from 1 review
no estimate extracted
1 study · 9 participants
Very low