Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

Four per cent chlorhexidine + hand hygiene promotion vs usual care

Authors reported adverse outcomes (events without hospitalisation) · Neonates and caregivers

It is very uncertain whether four per cent chlorhexidine + hand hygiene promotion changes authors reported adverse outcomes (events without hospitalisation) compared with usual care (very low certainty).

1 finding from 1 review

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose that meets total daily nutritional requirements vs as a supplement to the usual diet

Relapse during intervention defined as admission to inpatient therapeutic care or recurrence of oedema or systematic infections during the study period, and dropouts during intervention period · children aged 6 months‐5 years with SAM (1 study included HIV‐uninfected children; 1 study included HIV‐infected children), all of whom…

Standard ready‐to‐use therapeutic food (RUTF) provided at a dose… may leads to lower relapse during intervention defined as admission to inpatient… compared with as a supplement to the usual diet (low certainty).

1 finding from 1 review

Enhanced multidisciplinary team (EMDT) vs usual care

Proportion of participants developing a new pressure ulcer · people with pressure ulcers residing in long‐term‐care facilities

It is very uncertain whether enhanced multidisciplinary team (EMDT) changes pressure ulcer incidence rate compared with usual care (very low certainty).

1 finding from 1 review

Enhanced multidisciplinary team (EMDT) vs usual care

Number of pressure ulcers healed · people with pressure ulcers residing in long‐term‐care facilities

It is very uncertain whether enhanced multidisciplinary team (EMDT) changes number of pressure ulcers healed compared with usual care (very low certainty).

1 finding from 1 review