Cochrane · systematic review · CD012882

Integrated community case management of childhood illness in low‐ and middle‐income countries

Oliphant, NP, Manda, S, Daniels, K, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 6 · 54.5%Very low 4 · 36.4%Low 1 · 9.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: integrated community case management versus usual facility services

Population: children U5
7 questions
OutcomeEffectEvidenceStatus / GRADE
Any iCCM illness
Summary of findings: integrated community case management vs usual facility services
RR 0.96 [0.77, 1.19]5898 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Quality of care
Summary of findings: integrated community case management vs usual facility services
no estimate extracted2 participantsUngraded
Mortality
Summary of findings: integrated community case management vs usual facility services
no estimate extracted4 participantsUngraded
Neonatal mortality rate
Summary of findings: integrated community case management vs usual facility services
HR 1.01 [0.77, 1.33]65209 participantsLow
Downgraded: imprecision, inconsistency, indirectness
Infant mortality rate
Summary of findings: integrated community case management vs usual facility services
HR 0.98 [0.72, 1.34]65209 participantsVery low
Downgraded: imprecision, inconsistency, indirectness
U5 mortality rate
Summary of findings: integrated community case management vs usual facility services
1.16 [0.99, 1.36]4729 participantsVery low
Downgraded: imprecision, indirectness
Adverse events
Summary of findings: integrated community case management vs usual facility services
no estimate extracted5 participantsUngraded

Summary of findings: integrated community case management versus usual facility services plus CCM for malaria

Population: children U5
4 questions
OutcomeEffectEvidenceStatus / GRADE
Any iCCM illness
Summary of findings: integrated community case management vs usual facility services plus CCM
RR 1.59 [0.66, 3.87]7876 participantsVery low
Downgraded: risk of bias, imprecision
Quality of care
Summary of findings: integrated community case management vs usual facility services plus CCM
no estimate extracted2 participantsUngraded
Mortality
Summary of findings: integrated community case management vs usual facility services plus CCM
no estimate extracted4 participantsUngraded
Adverse events
Summary of findings: integrated community case management vs usual facility services plus CCM
no estimate extracted5 participantsUngraded