Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

579 questions · 601 findings · 56 reviews

No studies found 143 · 23.8%GRADE not reported 69 · 11.5%Very low 101 · 16.8%Low 142 · 23.6%Moderate 116 · 19.3%High 30 · 5%

Does normal saline flushing in long‐term central venous catheters (CVC) prevent occlusion vs heparin flushing

CVC occlusion rate per 1000 catheter days Ability to infuse solution through CVC · infants and children with a long‐term CVC

It is very uncertain whether does normal saline flushing in long‐term central venous catheters… changes CVC occlusion rate per 1000 catheter days: ability to infuse… compared with heparin flushing (very low certainty).

1 finding from 1 review

Does normal saline flushing in long‐term central venous catheters (CVC) prevent occlusion vs heparin flushing

CVC‐associated blood stream infection rate per 1000 catheter days Incidence of positive blood culture · infants and children with a long‐term CVC

Does normal saline flushing in long‐term central venous catheters… showed no clear difference in CVC‐associated blood stream infection rate per 1000 catheter days:… compared with heparin flushing (low certainty).

1 finding from 1 review

Indwelling urethral catheterisation vs suprapubic catheterisation

Number of participants with symptomatic UTI · Adults with short‐term catheterisation

It is very uncertain whether indwelling urethral catheterisation changes number of participants with symptomatic UTI compared with suprapubic catheterisation (very low certainty).

1 finding from 1 review

Indwelling urethral catheterisation vs suprapubic catheterisation

Asymptomatic bacteruria · Adults with short‐term catheterisation

It is very uncertain whether indwelling urethral catheterisation changes asymptomatic bacteruria compared with suprapubic catheterisation (very low certainty).

1 finding from 1 review

Indwelling urethral catheterisation vs suprapubic catheterisation

Number of participants with pain · Adults with short‐term catheterisation

Indwelling urethral catheterisation may leads to higher number of participants with pain compared with suprapubic catheterisation (low certainty).

1 finding from 1 review

Maintenance LTRA vs placebo

Number of participants experiencing one or more episode requiring treatment with oral steroids · episodic viral wheeze in children

Maintenance LTRA showed no clear difference in number of participants experiencing one or more episode requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Maintenance LTRA vs placebo

Number of participants experiencing one or more episodes requiring ED visit · episodic viral wheeze in children

Maintenance LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Maintenance LTRA vs placebo

Number of participants experiencing one or more episodes requiring hospital admission · episodic viral wheeze in children

Maintenance LTRA showed no clear difference in number of participants experiencing one or more episodes requiring… compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Death or hospital admission · Children with anaemia

The intervention showed no clear difference in death or hospital admission (moderate certainty).

1 finding from 1 review