Cochrane · systematic review · CD013496
Intermittent fasting for the prevention of cardiovascular disease
Allaf, M, Elghazaly, H, Mohamed, OG, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
24
current version
GRADE rated
6
No studies
18
Included studies
NR
No studies 18 · 75%Ungraded 0 · 0%Very low 3 · 12.5%Low 3 · 12.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
IF compared to ad libitum (short term) for the prevention of cardiovascular disease
Population: the prevention of cardiovascular disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes (4 to 12 weeks IF vs ad libitum (short term) | no estimate extracted | NR | No studies |
All‐cause mortality IF vs ad libitum (short term) | no estimate extracted | NR | No studies |
CV Mortality IF vs ad libitum (short term) | no estimate extracted | NR | No studies |
Stroke IF vs ad libitum (short term) | no estimate extracted | NR | No studies |
MI IF vs ad libitum (short term) | no estimate extracted | NR | No studies |
Heart failure IF vs ad libitum (short term) | no estimate extracted | NR | No studies |
Absolute change in body weight (kg) (4 to 12 weeks IF vs ad libitum (short term) | no estimate extracted | 7 studies · 224 participants | Low Downgraded: inconsistency |
Absolute change in Glucose (mmol/L) (8 to 12 weeks IF vs ad libitum (short term) | no estimate extracted | 3 studies · 95 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
IF compared to CER (short term) for the prevention of cardiovascular disease
Population: the prevention of cardiovascular disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes (4 to 12 weeks IF vs CER (short term) | no estimate extracted | NR | No studies |
All‐cause mortality IF vs CER (short term) | no estimate extracted | NR | No studies |
CV Mortality IF vs CER (short term) | no estimate extracted | NR | No studies |
Stroke IF vs CER (short term) | no estimate extracted | NR | No studies |
MI IF vs CER (short term) | no estimate extracted | NR | No studies |
Heart failure IF vs CER (short term) | no estimate extracted | NR | No studies |
Absolute change in body weight (kg) (4 to 12 weeks IF vs CER (short term) | no estimate extracted | 10 studies · 719 participants | Very low Downgraded: inconsistency |
Absolute change in Glucose (mmol/L) (4 to 12 weeks IF vs CER (short term) | no estimate extracted | 9 studies · 582 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
IF compared to CER (medium term) for the prevention of cardiovascular disease
Population: the prevention of cardiovascular disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes (4 months ‐ 6 months IF vs CER (medium term) | no estimate extracted | NR | No studies |
All‐cause mortality IF vs CER (medium term) | no estimate extracted | NR | No studies |
CV Mortality IF vs CER (medium term) | no estimate extracted | NR | No studies |
Stroke IF vs CER (medium term) | no estimate extracted | NR | No studies |
MI IF vs CER (medium term) | no estimate extracted | NR | No studies |
Heart failure IF vs CER (medium term) | no estimate extracted | NR | No studies |
Absolute change in body weight (kg) (4 months ‐ 6 months IF vs CER (medium term) | no estimate extracted | 4 studies · 279 participants | Low Downgraded: risk of bias |
Absolute change in glucose (mmol/L) (4 months ‐ 6 months IF vs CER (medium term) | no estimate extracted | 4 studies · 279 participants | Low Downgraded: risk of bias |