Does normal saline flushing in long‐term central venous catheters (CVC) prevent occlusion vs heparin flushing: CVC‐associated blood stream infection rate per 1000 catheter days Incidence of positive blood culture
Does normal saline flushing in long‐term central venous catheters… showed no clear difference in CVC‐associated blood stream infection rate per 1000 catheter days:… compared with heparin flushing (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Does normal saline flushing in long‐term central venous catheters (CVC) prevent occlusion vs heparin flushing CVC‐associated blood stream infection rate per 1000 catheter days: incidence of positive blood culture · infants and children with a long‐term CVC Does normal saline flushing in long‐term central venous catheters… showed no clear difference in CVC‐associated blood stream infection rate per 1000 catheter days:… compared with heparin flushing (low certainty). Normal saline (0.9% sodium chloride) versus heparin intermittent flushing for the prevention of occlusion in… (2020) · Cochrane Headline outcomes only | Rate ratio 1.48 [0.24, 9.37] | 2 studies · 231 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Normal saline (0.9% sodium chloride) versus heparin intermittent flushing for the prevention of occlusion in long‐term central venous… 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.