evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Intensive insulin therapy vs conventional insulin therapy

Occurrence of CIP/CIM ‐ in screened population · critically ill patients

Intensive insulin therapy probably leads to lower occurrence of CIP/CIM ‐ in screened population compared with conventional insulin therapy (moderate certainty).

1 finding from 1 review

Intensive insulin therapy vs conventional insulin therapy

Death ‐ at 30 days after ICU admission, in total population randomised · critically ill patients

Intensive insulin therapy showed no clear difference in death ‐ at 30 days after ICU admission, in total population randomised compared with conventional insulin therapy (high certainty).

1 finding from 1 review

Intensive insulin therapy vs conventional insulin therapy

Death ‐ at 180 days after ICU admission, in total population randomised · critically ill patients

Intensive insulin therapy showed no clear difference in death ‐ at 180 days after ICU admission, in total population… compared with conventional insulin therapy (moderate certainty).

1 finding from 1 review

Intensive insulin therapy vs conventional insulin therapy

Serious adverse events, ‐ in total population randomised ‐ hypoglycaemia · critically ill patients

Intensive insulin therapy leads to higher serious adverse events, ‐ in total population randomised ‐… compared with conventional insulin therapy (high certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

Global cognitive function (defined as reduction of at least 3 points in MMSE) · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in global cognitive function (defined as reduction of at least 3 points… compared with standard glycaemic control (moderate certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

Incidence of dementia · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in incidence of dementia (defined as dementia according to DSM‐IV) compared with standard glycaemic control (low certainty).

1 finding from 1 review

Dose‐intensified chemotherapy vs ABVD‐like chemotherapy (with or without radiotherapy

Secondary malignant neoplasms · Patients with untreated Hodgkin lymphoma (advanced stages)

Dose‐intensified chemotherapy showed no clear difference in secondary malignant neoplasms compared with ABVD‐like chemotherapy (with or without radiotherapy (low certainty).

1 finding from 1 review

Dose‐intensified chemotherapy vs ABVD‐like chemotherapy (with or without radiotherapy

Death · Patients with untreated Hodgkin lymphoma (advanced stages)

Dose‐intensified chemotherapy showed no clear difference in death compared with ABVD‐like chemotherapy (with or without radiotherapy (moderate certainty).

1 finding from 1 review

Dose‐intensified chemotherapy vs ABVD‐like chemotherapy (with or without radiotherapy

Progression/relapse · Patients with untreated Hodgkin lymphoma (advanced stages)

Dose‐intensified chemotherapy probably leads to lower progression/relapse compared with ABVD‐like chemotherapy (with or without radiotherapy (moderate certainty).

1 finding from 1 review