Intensive glycaemic control vs conventional glucose control: Global cognitive function (defined as reduction of at least 3 points in MMSE)
Intensive glycaemic control showed no clear difference in global cognitive function (defined as reduction of at least 3 points… compared with standard glycaemic control (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intensive glycaemic control vs standard glycaemic control Global cognitive function (defined as reduction of at least 3 points in MMSE) · patients with Type 2 diabetes Intensive glycaemic control showed no clear difference in global cognitive function (defined as reduction of at least 3 points… compared with standard glycaemic control (moderate certainty). Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia (2017) · Cochrane Headline outcomes only | RR 0.98 [0.88, 1.08] | 1 study · 11140 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.