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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,518 questions in 135 reviews · Infectious Diseases
current versionsNo studies 135 · 8.9%Ungraded 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Stillbirth · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 0.97 [0.64, 1.49] | 3 studies · 2703 participants | Low |
Intervention NR Perinatal mortality · Pregnant women (parity 0‐1) Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no… (2014) · Cochrane | RR 0.73 [0.54, 1] | 2 studies · 1620 participants | Low |
Intervention NR Death · Patients with dengue‐related shock Corticosteroids for dengue infection (2014) · Cochrane | RR 0.68 [0.42, 1.11] | 4 studies · 284 participants | Very low |
Intervention NR Ascitis · Patients with dengue infection at an early stage Corticosteroids for dengue infection (2014) · Cochrane | RR 0.12 [0.01, 2.13] | 1 study · 178 participants | Very low |
Intervention NR ICU admission · Patients with dengue infection at an early stage Corticosteroids for dengue infection (2014) · Cochrane | RR 0.88 [0.38, 1.99] | 2 studies · 286 participants | Very low |
Intervention NR Need for blood transfusion · Patients with dengue‐related shock Corticosteroids for dengue infection (2014) · Cochrane | RR 1.08 [0.52, 2.24] | 2 studies · 89 participants | Very low |
Intervention NR Pulmonary haemorrhage · Patients with dengue‐related shock Corticosteroids for dengue infection (2014) · Cochrane | RR 0.97 [0.06, 14.82] | 1 study · 63 participants | Very low |
Intervention NR Convulsions · Patients with dengue‐related shock Corticosteroids for dengue infection (2014) · Cochrane | RR 6.79 [0.36, 126.24] | 1 study · 63 participants | Very low |
Intervention NR Days in hospital · Patients with dengue‐related shock Corticosteroids for dengue infection (2014) · Cochrane | no estimate extracted | 1 study · 63 participants | Very low |
Intervention NR Death · Patients with dengue infection at an early stage Corticosteroids for dengue infection (2014) · Cochrane | no estimate extracted | 4 studies · 664 participants | Low |
Intervention NR Severe dengue: shock · Patients with dengue infection at an early stage Corticosteroids for dengue infection (2014) · Cochrane | RR 1.3 [0.48, 3.51] | 2 studies · 286 participants | Very low |
Intervention NR Severe dengue: severe bleeding · Patients with dengue infection at an early stage Corticosteroids for dengue infection (2014) · Cochrane | RR 1.51 [0.24, 9.43] | 2 studies · 425 participants | Very low |
Intervention NR Severe thrombocytopaenia11 · Patients with dengue infection at an early stage Corticosteroids for dengue infection (2014) · Cochrane | RR 1.51 [0.31, 7.28] | 1 study · 225 participants | Very low |
Intervention NR Attendance at single clinic appointment · People on TB treatment Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment (2014) · Cochrane | RR 1.32 [1.1, 1.59] | 1 study · 615 participants | Low |
Intervention NR Completion of TB treatment · People on TB treatment Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment (2014) · Cochrane | RR 1.14 [1.02, 1.27] | 1 study · 92 participants | Low |
Intervention NR Attendance at single clinic appointment · People on TB treatment Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment (2014) · Cochrane | RR 5.04 [1.61, 15.78] | 1 study · 52 participants | Low |
Intervention NR Completion of TB treatment · People on TB treatment Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment (2014) · Cochrane | RR 1.17 [1.11, 1.24] | 2 studies · 680 participants | Moderate |
Intervention NR Attendance at clinic · People at risk of TB Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment (2014) · Cochrane | RR 1.06 [0.92, 1.21] | 3 studies · 1189 participants | Low |
Intermittent short‐course anti‐TB regimens vs daily anti‐TB regimens Cure · Children with TB1 Intermittent versus daily therapy for treating tuberculosis in children (2014) · Cochrane | RR 1.01 [0.94, 1.1] | 4 studies · 465 participants | Very low |
Intermittent short‐course anti‐TB regimens vs daily anti‐TB regimens Death from any cause · Children with TB1 Intermittent versus daily therapy for treating tuberculosis in children (2014) · Cochrane | RR 1.52 [0.26, 8.96] | 2 studies · 213 participants | Very low |
Intermittent short‐course anti‐TB regimens vs daily anti‐TB regimens Relapse · Children with TB1 Intermittent versus daily therapy for treating tuberculosis in children (2014) · Cochrane | RR 3.68 [0.15, 89.33] | 1 study · 214 participants | Very low |
Intermittent short‐course anti‐TB regimens vs daily anti‐TB regimens Adherence to treatment · Children with TB1 Intermittent versus daily therapy for treating tuberculosis in children (2014) · Cochrane | RR 1.04 [0.97, 1.11] | 4 studies · 458 participants | Very low |
Intermittent short‐course anti‐TB regimens vs daily anti‐TB regimens Treatment‐limiting adverse events · Children with TB1 Intermittent versus daily therapy for treating tuberculosis in children (2014) · Cochrane | RR 0.4 [0.06, 2.6] | 4 studies · 441 participants | Very low |
Antimicrobial drugs vs placebo/no treatment Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 19 studies · 1013 participants | Moderate |
Azithromycin vs erythromycin Stool volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 2 studies · 172 participants | Moderate |
Azithromycin vs erythromycin Bacteriological failure · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | RR 1.56 [0.8, 3.02] | 2 studies · 179 participants | Low |
Tetracycline vs doxycycline Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 3 studies · 230 participants | Moderate |
Tetracycline vs doxycycline Stool volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 3 studies · 336 participants | Moderate |
Tetracycline vs doxycycline Bacteriological failure · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | RR 0.2 [0.06, 0.68] | 2 studies · 198 participants | Moderate |
Tetracycline vs quinolones Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 3 studies · 259 participants | Moderate |
Tetracycline vs quinolones Stool volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 2 studies · 236 participants | Low |
Tetracycline vs quinolones Bacteriological failure · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | RR 0.99 [0.14, 6.82] | 2 studies · 234 participants | Low |
Doxycycline vs quinolones Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 3 studies · 126 participants | Low |
Doxycycline vs quinolones Stool volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 4 studies · 435 participants | Low |
Antimicrobial drugs vs placebo/no treatment Stool volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 18 studies · 1042 participants | Moderate |
Doxycycline vs quinolones Bacteriological failure · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | RR 5.84 [2.7, 12.65] | 4 studies · 386 participants | Low |
Short vs long duration of antimicrobials Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | MD 0.34 | 7 studies · 431 participants | Low |
Short vs long duration of antimicrobials Stool Volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 8 studies · 496 participants | Low |
Short vs long duration of antimicrobials Bacteriological failure · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | RR 1.53 [1.01, 2.32] | 9 studies · 672 participants | Low |
Antimicrobial drugs vs placebo/no treatment Hydration fluid requirements · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 11 studies · 1201 participants | Moderate |
Antimicrobial drugs vs placebo/no treatment Duration of pathogen secretion · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 12 studies · 740 participants | Moderate |
Antimicrobial drugs vs placebo/no treatment Deaths · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 7 studies · 299 participants | Ungraded |
Azithromycin vs ciprofloxacin Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 2 studies · 375 participants | Moderate |
Azithromycin vs ciprofloxacin Stool volume · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 1 study · 195 participants | Low |
Azithromycin vs ciprofloxacin Bacteriological failure · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | RR 0.23 [0.16, 0.34] | 2 studies · 375 participants | Low |
Azithromycin vs erythromycin Diarrhoea duration · Adults and children with cholera diarrhoea Antimicrobial drugs for treating cholera (2014) · Cochrane | no estimate extracted | 2 studies · 179 participants | Moderate |
Intervention NR Patients still unwell at day 4 to 7 · People with fever Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings (2014) · Cochrane | RR 0.9 [0.69, 1.17] | 5 studies · 6990 participants | Low |
Intervention NR Patients prescribed antimalarials · People with fever Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings (2014) · Cochrane | RR 0.62 [0.52, 0.73] | 7 studies · 17287 participants | Moderate |
Intervention NR Patients prescribed antibiotics · People with fever Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings (2014) · Cochrane | no estimate extracted | 5 studies · 13573 participants | Very low |
Intervention NR Patients with microscopically confirmed malaria not receiving antimalarials · People with fever Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings (2014) · Cochrane | RR 1.21 [0.64, 2.28] | 1 study · 1280 participants | Low |