Total mortality · adult patients with hypertension
Lower BP target showed no clear difference in total mortality compared with standard BP target (high certainty).
1 finding from 1 review
RR 0.95 [0.86, 1.05]
Studies not reported
High
Total serious adverse events№ of participants: 18165(6 RCTs) · adult patients with hypertension
Lower BP target showed no clear difference in total serious adverse events№ of participants: 18165(6 RCTs) compared with standard BP target (moderate certainty).
1 finding from 1 review
RR 1.04 [0.99, 1.08]
Studies not reported
Moderate
Myocardial infarction · adult patients with hypertension
Lower BP target may leads to lower myocardial infarction№ of participants: 38,198(8 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.84 [0.73, 0.96]
Studies not reported
Low
Stroke · adult patients with hypertension
Lower BP target showed no clear difference in stroke№ of participants: 37,087(7 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.88 [0.77, 1.01]
Studies not reported
Low
Congestive heart failure · adult patients with hypertension
Lower BP target may leads to lower congestive heart failure№ of participants: 15,859(5 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.75 [0.6, 0.92]
Studies not reported
Low
Other serious adverse events · adult patients with hypertension
Lower BP target may leads to higher other serious adverse events compared with standard BP target (low certainty).
1 finding from 1 review
RR 1.44 [1.32, 1.59]
Studies not reported
Low
Body fatness (represented by body weight, kg) · Adults (general population)
1 finding from 1 review
Body‐mass index (BMI) · Adults (general population)
1 finding from 1 review
Waist circumference · Adults (general population)
1 finding from 1 review
Body fatness (represented by percentage body fat) · Adults (general population)
1 finding from 1 review
Potential harms ‐ serum lipids, mmol/L · Adults (general population)
1 finding from 1 review
Blood pressure · Adults (general population)
1 finding from 1 review
Potential harms ‐ quality of life (QoL) · Adults (general population)
1 finding from 1 review
Failed CPAP · preterm infants with apnea
It is very uncertain whether infant Flow CPAP changes failed CPAP compared with medijet CPAP (very low certainty).
1 finding from 1 review
Mean apnoea events · preterm infants with apnea
1 finding from 1 review
no estimate extracted
24 participants
GRADE not reported
Adverse events · preterm infants with apnea
1 finding from 1 review
2
2 participants
GRADE not reported
Neurodevelopmental outcomes · preterm infants with apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death (any cause) · adults with DKD
Low protein diet showed no clear difference in death (any cause) compared with usual or unrestricted protein diet (low certainty).
1 finding from 1 review
Kidney failure · adults with DKD
Low protein diet showed no clear difference in kidney failure compared with usual or unrestricted protein diet (low certainty).
1 finding from 1 review
Change in GFR · adults with DKD
1 finding from 1 review